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Displaying results 1641 - 1650 of 10000 in total
  1. Drug

    Prednicarbate

    go.drugbank.com/drugs/DB01130
    Approved

    It has a favorable benefit-risk ratio, with an inflammatory action similar to that of a medium potency corticosteroid, but with a low potential to cause skin atrophy. … IL-1a is also found in fibroblasts, where it is responsible for proliferation, collagenase induction and IL-6 synthesis, which are related to skin thickness.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: DERMATOP 2.5 MG/G KREM, 30 G, DERMATOP 2.5 MG/G MERHEM, 30 G
  2. Drug

    Tiaprofenic acid

    go.drugbank.com/drugs/DB01600
    Approved

    It belongs to the _arylpropionic acid_ (profen) group of nonsteroidal anti-inflammatory drugs (NSAIDs).

    Synonyms: 2-(5-Benzyl-2-thienyl)propionsäure, 2-(5-Benzoyl-thiophen-2-yl)-propionic acidProducts: SURGAM 300 MG TABLET, 20 ADET, SURGAM RETARD 300 MG TABLET, 20 ADET
  3. Drug

    Polyvinyl alcohol

    go.drugbank.com/drugs/DB11060
    Approved

    Polyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes [L2826]. … Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol.

    Mixtures: SICCAPROTECT 10 ML GOZ DAMLASI, FULLFRESH 5,60 MG/2,40 MG TEK DOZLUK GÖZ DAMLASI, ÇÖZELTİProducts: VERILUB® 14 MG/MLSOLUCIÓN OFTÁLMICA, ALCOHOL POLIVINÍLICO 14MG/ML SOLUCIÓN OFTÁLMICA
  4. Drug

    Loteprednol etabonate

    go.drugbank.com/drugs/DB14596
    Approved

    Moreover, LE was purposefully engineered to be a 'soft drug', one that is designed to be active locally at the site of administration and then rapidly metabolized to inactive components after eliciting … enhance patient compliance and simplified dosing compared to all other similar ocular steroids that are dosed four times daily [L4545].

    Mixtures: TOBRALOT 5 MG+3 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET, ZYLET OFTALMIK SUSPANSIYON, 5 MLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  5. Drug

    Brivudine

    go.drugbank.com/drugs/DB03312
    ApprovedInvestigational

    Brivudine is used in the treatment of herpes zoster. Although not approved in the U.S. or Canada, it is approved in several European countries.

    Synonyms: (E)-5-(2-Bromovinyl)-deoxyuridineProducts: Mevir 125 mg Tabletten, Brivudin Aristo 125 mg Tabletten
  6. Drug

    Midostaurin

    go.drugbank.com/drugs/DB06595
    ApprovedInvestigational

    It was approved on April 28, 2017 and has shown to increase the overall survival rate in patients with AML as an adjunct therapy along with chemotherapeutic agents.

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP2B6 InducersProducts: RYDAPT (25 MG SOFT CAPSULES), RYDAPT 25 MG YUMUŞAK KAPSÜL, 112 ADET
  7. Drug

    Prucalopride

    go.drugbank.com/drugs/DB06480
    ApprovedInvestigational

    [A37348] The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies. … [A40254] Prucalopride was developed by Shire Development LLC and approved for use in Europe in 2009,[A40250] in Canada on December 7, 2011 and by the FDA on December 17, 2018.[L4880]

    Categories: Serotonin 5-HT4 Receptor Agonists, Cytochrome P-450 SubstratesProducts: Resolor Film-coated Tablet 2 mg, Resolor Film-coated Tablet 1 mg
  8. Drug

    Valbenazine

    go.drugbank.com/drugs/DB11915
    ApprovedInvestigational

    The reduction in chorea severity was observed as early as 2 weeks after starting treatment with an initial dose of 40 mg.[L47910] … [A261165] On April 2017, valbenazine was approved by the FDA under the brand name INGREZZA as the first and only approved treatment for adults with Tardive Dyskinesia (TD).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: REMLEAS HARD CAPSULES 40 MG
  9. Drug

    Primidone

    go.drugbank.com/drugs/DB00794
    ApprovedVet approved

    Primidone is an anticonvulsant used to treat essential tremor as well as grand mal, psychomotor, and focal epileptic seizures. … [L11112] Primidone was developed by J Yule Bogue and H C Carrington in 1949.[A189522] Primidone was granted FDA Approval on 8 March 1954.[L11112]

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersSynonyms: 5-Phenyl-5-ethyl-Hexahydropyrimidine-4,6-dione
  10. Drug

    Meldonium

    go.drugbank.com/drugs/DB13723
    Investigational

    Products: SATURID 100 MG/ ML I.V. ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL