This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Meldonium
- DrugBank Accession Number
- DB13723
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Meldonium (DB13723)
- Weight
- Average: 146.19
Monoisotopic: 146.105527699 - Chemical Formula
- C6H14N2O2
- Synonyms
- Meldonium
- External IDs
- MET-88
Pharmacology
- Indication
Not Available
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Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
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Categories
- ATC Codes
- C01EB22 — Meldonium
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as beta amino acids and derivatives. These are amino acids having a (-NH2) group attached to the beta carbon atom.
- Kingdom
- Organic compounds
- Super Class
- Organic acids and derivatives
- Class
- Carboxylic acids and derivatives
- Sub Class
- Amino acids, peptides, and analogues
- Direct Parent
- Beta amino acids and derivatives
- Alternative Parents
- Carboxylic acid salts / Monocarboxylic acids and derivatives / Carboxylic acids / Organopnictogen compounds / Organonitrogen compounds / Organic salts / Organic oxides / Hydrocarbon derivatives / Carbonyl compounds
- Substituents
- Aliphatic acyclic compound / Beta amino acid or derivatives / Carbonyl group / Carboxylic acid / Carboxylic acid salt / Hydrocarbon derivative / Monocarboxylic acid or derivatives / Organic nitrogen compound / Organic oxide / Organic oxygen compound
- Molecular Framework
- Aliphatic acyclic compounds
- External Descriptors
- a small molecule (CPD-10661)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 73H7UDN6EC
- CAS number
- 76144-81-5
- InChI Key
- PVBQYTCFVWZSJK-UHFFFAOYSA-N
- InChI
- InChI=1S/C6H14N2O2/c1-8(2,3)7-5-4-6(9)10/h7H,4-5H2,1-3H3
- IUPAC Name
- 3-(2,2,2-trimethylhydrazin-2-ium-1-yl)propanoate
- SMILES
- C[N+](C)(C)NCCC([O-])=O
References
- General References
- Not Available
- External Links
- ChemSpider
- 110405
- BindingDB
- 50007906
- ChEBI
- 131843
- ChEMBL
- CHEMBL2104708
- Wikipedia
- Meldonium
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 4 Completed Treatment Asthenia / Cognitive Impairment (CI) / Coronavirus Disease 2019 (COVID‑19) / Functional MRI 1 4 Completed Treatment Asthenia / Coronavirus Disease 2019 (COVID‑19) 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Injection, solution Intravenous 100 mg/ml - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 20.2 mg/mL ALOGPS logP -2.6 ALOGPS logP -1.4 Chemaxon logS -0.99 ALOGPS pKa (Strongest Acidic) 4.14 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 52.16 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 61.82 m3·mol-1 Chemaxon Polarizability 15.62 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted GC-MS Spectrum - GC-MS Predicted GC-MS Not Available
Drug created at June 23, 2017 20:47 / Updated at February 21, 2021 18:54