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Lucinactant
go.drugbank.com/drugs/DB04897ApprovedIt is completely devoid of animal-derived components. FDA approved on March 6, 2012. … More specifically, it mimics the C-terminal amphipathic helical domain of this protein.
Chlormadinone acetate
go.drugbank.com/drugs/DB15903ApprovedWithdrawnHowever, the use of these drugs was associated with the development of mammary tumors in dogs. In 1972, the FDA withdrew its approval for the use of chlormadinone acetate in all products. … Chlormadinone acetate is a progesterone derivative first synthesized in 1961.
Mixtures: BELARA film-coated tablet 0.03mg/2mg, LUTORAL-EEliglustat
go.drugbank.com/drugs/DB09039ApprovedInvestigational[L41404,A7634] Eliglustat was approved by the FDA in August 2014 as an oral substrate reduction therapy for the first-line treatment of type 1 Gaucher disease. … [A3752,L41404] Gaucher disease is a rare genetic disorder characterized by the deficiency of acid β-glucosidase, an enzyme that converts glucosylceramide into glucose and ceramide.
Synonyms: N-[(1R,2R)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(1-pyrrolidinyl)-2-propanyl]octanamideProducts: ELUXAT 84 MG SERT KAPSÜL, CERDELGA® 84 MG CÁPSULA DURANandrolone decanoate
go.drugbank.com/drugs/DB08804ApprovedIllicitInvestigational[A233789,A233849,L32564,L9464] The process for creating esters of [nandrolone] was patented in Spain in 1959[L33244] and in 1960, it was described as having a long duration of action and strong anabolic … Nandrolone decanoate, also known as nandrolone caprinate, is an alkylated anabolic steroid indicated in the management of anemia of renal insufficiency and as an adjunct therapy in the treatment of senile
Products: DECA - DURABOLIN® 50 MG, PARABOLIN 25 MG AMPUL, 2 ADETMilnacipran
go.drugbank.com/drugs/DB04896ApprovedInvestigationalyet approved the agent for such treatment, citing lack of robust evidence of efficacy, insufficient demonstration of maintenance of effect, and other concerns [F3928, F3934]. … important role in the mitigation of pain signals in the descending inhibitory pain pathways in the brain and spinal cord [A175759, A175843, A175846].
Products: Ixel 25 mg - Kapseln, Ixel 50 mg - KapselnFenproporex
go.drugbank.com/drugs/DB01550ApprovedIllicitWithdrawnFenproporex is an orally active stimulant drug, which was developed in the 1960s. It is used as an appetite suppressant and a treatment for obesity. … It is listed as an illicit substance in many countries due to addiction issues and listed as a prohibited substance by the World Anti-Doping Agency.
Rutin
go.drugbank.com/drugs/DB01698ApprovedInvestigationalA flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.
Mixtures: Nutriforte Non-Acidic Vitamin C 1000 mg with BioflavonoidsColestipol
go.drugbank.com/drugs/DB00375Approved, patients who take complicated medication regimens, experience constipation or biliary obstruction, etc. may not be good candidates for using the agent owing to its physical effects on the gut. … [FDA Label, F4555, F4567, L6262] Alternatively, colestipol predominantly elicits its activities within the gut environment because it undergoes little absorption and metabolism.
Categories: Compounds used in a research, industrial, or household settingLepirudin
go.drugbank.com/drugs/DB00001ApprovedWithdrawnat position 1 (N-terminal end). … [L41539] Lepirudin is produced in yeast cells and is identical to natural hirudin except for the absence of sulfate on the tyrosine residue at position 63 and the substitution of leucine for isoleucine
Segesterone acetate
go.drugbank.com/drugs/DB14583ApprovedIt is commonly sold under the brand names Nestorone and Elcometrine and serves as an active component in hormonal contraceptives. … Segesterone acetate is not an orally active compound, but it is proved to be a potent anti-ovulatory agent when given in implants, vaginal rings or percutaneous gel [A37090].
Synonyms: 17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate