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Displaying results 1651 - 1660 of 10000 in total
  1. Drug

    Piritramide

    go.drugbank.com/drugs/DB12492
    ApprovedWithdrawn

    Piritramide is under investigation for the treatment of Colon Cancer and Minimal Residual Disease. Piritramide has been investigated for the supportive care of Pain, Postoperative and Postoperative Nausea and Vomiting.

    Products: Dipidolor 7,5 mg/ml Injektionslösung
  2. Drug

    Phendimetrazine

    go.drugbank.com/drugs/DB01579
    ApprovedIllicit

    Phendimetrazine is chemically related to amphetamines and is a Schedule III drug under the Convention on Psychotropic Substances and in the US since 1970.

    Synonyms: (2S,3S)-3,4-dimethyl-2-phenylmorpholineProducts: Fendique ER, Phendimetrazine Tartrate ER
  3. Drug

    Nepafenac

    go.drugbank.com/drugs/DB06802
    ApprovedInvestigational

    It is used to treat pain and inflammation associated with cataract surgery.

    Synonyms: 2-amino-3-benzoylbenzeneacetamideCategories: Selective Cyclooxygenase 2 Inhibitors (NSAIDs)
  4. Drug

    Ixazomib

    go.drugbank.com/drugs/DB09570
    ApprovedInvestigational

    [A264329] Ixazomib was approved by the FDA on November 20, 2015, making it the first oral proteasome inhibitor approved in the US. … [A264319] It was later approved by Health Canada on August 3, 2016,[L51239] and by the EMA on November 21, 2016.

    Synonyms: 2-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-5-oxo-1,3,2-dioxaborolane-4,4-diacetic acid, BORONIC ACID, B-((1R)-1-((2-((2,5-DICHLOROBENZOYL)AMINO)ACETYL)AMINO)-3-METHYLBUTYL)-Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  5. Drug

    Naphazoline

    go.drugbank.com/drugs/DB06711
    Approved

    It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807]. … Naphazoline was first developed in 1942 as a nasal formulation for congestion[A176609].

    Mixtures: SULFARHIN BURUN MERHEMI, 20 G, OSMOCROM-N ®Categories: Adrenergic alpha-2 Receptor Agonists
  6. Drug

    Perflutren

    go.drugbank.com/drugs/DB00556
    ApprovedInvestigational

    The difference in density between the gas-filled bubbles and the blood around them creates an increased level of contrast visible in the resulting ultrasound image. … During echocardiography, activated Perflutren enhances images of the inner edges or borders of the heart, producing an improved image that may enable physicians to better diagnose patients.

    Categories: Compounds used in a research, industrial, or household settingProducts: CIPROFLOXACINO TABLETAS X 500 MG, Definity RT
  7. Drug

    alpha-Tocopherol succinate

    go.drugbank.com/drugs/DB14001
    ApprovedNutraceuticalVet approved

    The recommended dietary allowances (RDAs) for vitamin E alpha-tocopherol are: males = 4 mg (6 IU) females = 4 mg (6 IU) in ages 0-6 months, males = 5 mg (7.5 IU) females = 5 mg (7.5 IU) in ages 7-12 months … = 15 mg (22.4 IU) females = 15 mg (22.4 IU) pregnancy = 15 mg (22.4 IU) lactation = 19 mg (28.4 IU) in ages 14+ years [L2120].

    Synonyms: Vitamin E succinate, Vitamin E hemisuccinateMixtures: Vitamine E 400 Ui and Selenium 50, PreQue 10
  8. Drug

    Agalsidase alfa

    go.drugbank.com/drugs/DB15874
    ApprovedInvestigational

    [A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a contamination event in 2009. … [A220343] Agalsidase alfa was granted EMA approval on 3 August 2001.[L16413]

    Products: REPLAGAL CONCENTRATE FOR SOLUTION FOR INFUSION 1 MG/ML
  9. Drug

    Peppermint oil

    go.drugbank.com/drugs/DB11198
    ApprovedInvestigational

    It is also an active ingredient in topical analgesics for the relief of joint and muscle pain. Peppermint oil can be applied topically to temporarily relieve tension-type headache. … Peppermint oil is safe and well-tolerated at commonly recommended dosage [A33055].

    Mixtures: MENTOSEPTOL GARGARA, 100 ML, BUĞUMENTOL BUĞU, 40 GCategories: Herbs and Natural Products, Cytochrome P-450 CYP1A2 Inhibitors
  10. Drug

    Mitotane

    go.drugbank.com/drugs/DB00648
    ApprovedInvestigational

    It has been in use since 1959 for the treatment of inoperable adrenocortical carcinoma[A263010] and is used off-label for the management of Cushing's syndrome.[A263016] … Mitotane is an adrenolytic isomer of the insecticide dichlorodiphenyldichloroethane (DDD) - itself a metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and

    Synonyms: 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]-benzeneCategories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 Inducers