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Displaying results 1661 - 1670 of 10000 in total
  1. Drug

    Indapamide

    go.drugbank.com/drugs/DB00808
    ApprovedInvestigational

    The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor to all-cause mortality is hypertension. … agents may be required in order to achieve blood pressure targets.

    Mixtures: PERINDO/IN RAT T 5/1.25, PERINDO/IN RAT T 5/1.25Products: COMPRIMIDOS RECUBIERTOS DE LIBERACION PROLONGADA, INDAPAMIDA 1.5 MG TABLETA DE LIBERACION PROLONGADA
  2. Drug

    Abacavir

    go.drugbank.com/drugs/DB01048
    ApprovedInvestigational

    Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring. … In vivo, abacavir sulfate dissociates to its free base, abacavir.

    Mixtures: ABACAVIR E LAMIVUDINA LUPIN, ABACAVIR E LAMIVUDINA LUPINCategories: Antivirals used in combination for the treatment of HIV infections
  3. Drug

    Thyrotropin alfa

    go.drugbank.com/drugs/DB00024
    ApprovedInvestigationalVet approved

    The beta subunit (TSHB) bestows its receptor specificity due to the uniqueness to TSH. The amino acid sequence of thyrotropin alfa is identical to that of human pituitary thyroid stimulating hormone. … The alpha subunit of thyrotropin alfa, which is the effector region responsible for the stimulation of adenylate cyclase, displays close structural similarity with the alpha subunit of human chorionic

    Categories: Agents used to treat hypothyroidism
  4. Drug

    Normethadone

    go.drugbank.com/drugs/DB11609
    ApprovedIllicit

    It is marketed in Canada by Valeant under the tradename Cophylac.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  5. Drug

    Ceftizoxime

    go.drugbank.com/drugs/DB01332
    ApprovedWithdrawn

    It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders. … The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms.

    Products: E-ZOX
  6. Drug

    Droperidol

    go.drugbank.com/drugs/DB00450
    ApprovedInvestigationalVet approved

    It is used in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the … A butyrophenone with general properties similar to those of haloperidol.

    Categories: Adrenergic alpha-1 Receptor Antagonists, Dopamine D2 Receptor Antagonists
  7. Drug

    Desipramine

    go.drugbank.com/drugs/DB01151
    Approved

    The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. … TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin Receptor Antagonists
  8. Target

    Alpha-2 adrenergic receptors

    go.drugbank.com/bio_entities/BE0004864
    TargetHumans

    Alpha-2 adrenergic receptors are G protein-coupled receptors for catecholamines that activate the G(i/o) protein pathway, thereby promoting adenylyl cyclase inhibition, ERK1/2 stimulation, and voltage-gated calcium channels suppression (...

    Polypeptides: Alpha-2A adrenergic receptor, Alpha-2B adrenergic receptorSynonyms: Alpha-2 adrenergic receptor subtype C10, Alpha-2 adrenergic receptor subtype C2
  9. Drug

    Epicriptine

    go.drugbank.com/drugs/DB11275
    Approved

    [T195] To know more about the mixture please visit [DB01049] … Together with the alpha-dihydroergocryptine, it represents one-third of the ergoloid mesylate mixture. Epicriptine differs from the alpha form on the position of one methyl group.

  10. Drug

    Cyclophosphamide

    go.drugbank.com/drugs/DB00531
    ApprovedInvestigational

    Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. … It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep.