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Displaying results 1681 - 1690 of 10000 in total
  1. Drug

    Semaglutide

    go.drugbank.com/drugs/DB13928
    ApprovedInvestigational

    as the first approved drug for such use since 2014. … Semaglutide is a glucagon-like peptide 1 (GLP-1) analog used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and increased physical activity.

    Products: RYBELSUS 3 MG TABLET, 30 ADET, RYBELSUS 3 MG TABLET, 60 ADET
  2. Drug

    Thonzonium

    go.drugbank.com/drugs/DB09552
    Approved

    It is widely used as an additive to in ear and nasal drops to enhance dispersion and penetration of cellular debris and exudate, thereby promoting tissue contact of the administered medication. … A common pharmaceutical formulation of thonzonium bromide is cortisporin-TC ear drops. It is also reported that thonzonium also confers an antifungal property and antiresorptive effect on bone.

  3. Drug

    Emapalumab

    go.drugbank.com/drugs/DB14724
    ApprovedInvestigational

    Emapalumab, also known as NI-0501, is a fully human monoclonal antibody that targets interferon gamma. … [L4840] As well, emapalumab was given the status of PRIME by the EMA.[L4845]

    Categories: Agents reducing cytokine levels
  4. Drug

    Lotilaner

    go.drugbank.com/drugs/DB17992
    ApprovedInvestigationalVet approved

    Lotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds. … [L47546] Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and tick infestations in animals.

  5. Drug

    Milsaperidone

    go.drugbank.com/drugs/DB24348
    ApprovedInvestigational

    [A275426, A202004] Similarly, milsaperidone acts as an antagonist at dopamine D2 and 5-HT2A receptors,[A275427] as well as other adrenergic, dopamine, and serotonin receptor subtypes. … Milsaperidone is an atypical antipsychotic agent that rapidly interconverts to [iloperidone] in vivo.

  6. Drug

    Nabilone

    go.drugbank.com/drugs/DB00486
    ApprovedInvestigational

    This can be achieved through heating, smoking, vaporization, or baking of dried unfertilized female cannabis flowers. … CB2 receptors are mainly located in the peripheral nervous system and can be found on lymphoid tissue where they are involved in regulation of immune function [A32676].

    Products: Ran-nabilone
  7. Indication

    Tic Disorder, Combined Vocal and Multiple Motor

    go.drugbank.com/conditions/DBCOND0082267
    Drugs: Clonazepam · Clonidine · Fluphenazine · Guanfacine · Haloperidol · Olanzapine +1 more
    Synonyms: Gilles de la Tourette, Gilles de la Tourette's
  8. Drug

    Apalutamide

    go.drugbank.com/drugs/DB11901
    ApprovedInvestigational

    Higher prostate-specific antigen (PSA) and shorter PSA doubling time (PSA DT) are associated with a higher risk for metastases and death [A31846]. … Exerting an antitumor action, apalutamide blocking the effect of androgens that promote tumor growth.

  9. Drug

    Guanadrel

    go.drugbank.com/drugs/DB00226
    Approved

    Guanadrel is an antihypertensive agent and postganglionic adrenergic blocking agent.

  10. Drug

    Tivantinib

    go.drugbank.com/drugs/DB12200
    Investigational

    Tivantinib has been investigated in Solid Tumors.

    Categories: Proto-Oncogene Proteins c-met, antagonists & inhibitors