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Cilastatin
go.drugbank.com/drugs/DB01597ApprovedInvestigationalCilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4.
Salts: Cilastatin sodiumMixtures: IMIPENEM MONOHYDRATE - CILASTATIN SODIUM, IMIPENEM MONOHYDRATE / CILASTATIN SODIUMChlorothiazide
go.drugbank.com/drugs/DB00880ApprovedInvestigationalVet approvedA thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
Salts: Chlorothiazide sodiumCategories: Sodium Chloride Symporter Inhibitors, chlorothiazide and potassiumARGX-119
go.drugbank.com/drugs/DB18133InvestigationalARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK).
Synonyms: a fully humanized immunoglobulin gamma 1 (IgG1) agonistic monoclonal antibody (mAb) that specifically targets and activates MuSKGTP-506
go.drugbank.com/drugs/DB17682ExperimentalGTP-506 is a gene therapy formed by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and a therapeutic donor vector that inserts the OTC gene to provide
Synonyms: Non-replicating recombinant adeno-associated virus serotype rh79 (AAVrh.79) vectors: AAVrh79.TBG.M2PCSK9.WPRE.bGH and AAVrh79.hHDR.TBG.hOTCco.bGHFondaparinux
go.drugbank.com/drugs/DB00569ApprovedInvestigationalangina (UA) and non-ST segment elevation myocardial infarction (NSTEMI); and in the management of ST segment elevation myocardial infarction (STEMI). … Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule.
Salts: Fondaparinux sodiumCategories: Blood and Blood Forming OrgansMeclofenamic acid
go.drugbank.com/drugs/DB00939ApprovedInvestigationalVet approvedA non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
Salts: Meclofenamate sodiumCategories: Antiinflammatory and Antirheumatic Products, Topical Products for Joint and Muscular PainNipocalimab
go.drugbank.com/drugs/DB16257ApprovedInvestigational[L64042] It is an aglycosylated, fully human IgG1 monoclonal antibody that binds FcRn and blocks the receptor's recycling of immunoglobulin G (IgG), thereby lowering circulating IgG levels, including pathogenic
Synonyms: immunoglobulin G1-lambda, anti-[Homo sapiens FCGRT (Fc fragment of IgG receptor and transporter, neonatal Fc receptor, FcRn, transmembrane alpha chain of the neonatal receptor)], Homo sapiens monoclonalCategories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsFosphenytoin
go.drugbank.com/drugs/DB01320ApprovedInvestigationalIts main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials.
Salts: Fosphenytoin sodiumCategories: Phenytoin and Prodrugs, Sodium Channel BlockersSulfacetamide
go.drugbank.com/drugs/DB00634ApprovedAn anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Salts: Sulfacetamide sodiumMixtures: SODIUM SULFACETAMIDE and SULFUR, Sodium Sulfacetamide and SulfurPhenylbutyric acid
go.drugbank.com/drugs/DB06819ApprovedInvestigationalIt demonstrates a number of cellular and biological effects, such as relieving inflammation and acting as a chemical chaperone. … [A249035] It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders.[L386,L42105]
Salts: Sodium phenylbutyrateCategories: sodium phenylbutyrate and ursodoxicoltaurine, sodium phenylbutyrate