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Displaying results 161 - 165 of 165 in total
  1. Target

    Atrial natriuretic peptide receptor 3

    go.drugbank.com/bio_entities/BE0002426
    TargetHumans

    May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. … Acts as a regulator of osteoblast differentiation and bone growth by binding to its ligand osteocrin, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production

    Synonyms: ANP-C
  2. Target

    ADP/ATP translocase 2

    go.drugbank.com/bio_entities/BE0000709
    TargetHumans

    production and cause mitochondrial thermogenesis (By similarity). … ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (By similarity).

    Synonyms: ANT 2
  3. Target

    ADP/ATP translocase 1

    go.drugbank.com/bio_entities/BE0000599
    TargetHumans

    production and cause mitochondrial thermogenesis (By similarity). … In addition to its ADP:ATP antiporter activity, also involved in mitochondrial uncoupling and mitochondrial permeability transition pore (mPTP) activity (PubMed:31883789).

    Synonyms: ANT 1
  4. Target

    Pyruvate kinase PKM

    go.drugbank.com/bio_entities/BE0000088
    TargetHumans

    The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival (PubMed:15996096, PubMed:1854723, PubMed:20847263) … The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production (PubMed

    Synonyms: OIP-3
  5. Target

    Pyruvate Kinases

    go.drugbank.com/bio_entities/BE0009686
    EnzymeTargetHumans

    The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival (PubMed:15996096, PubMed:1854723, PubMed:20847263) … Pyruvate kinase that catalyzes the conversion of phosphoenolpyruvate to pyruvate with the synthesis of ATP, and which plays a key role in glycolysis (PubMed:11960989).

    Synonyms: OIP-3