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Displaying results 161 - 170 of 104418 in total
  1. Drug

    Trolamine salicylate

    go.drugbank.com/drugs/DB11079
    Approved

    As with other salicylates, trolamine salicylate is an inhibitor of cyclo-oxygenase (COX) enzymes with no reported selectivity towards a specific enzyme isoform. … Trolamine salicylate serves as an active ingredient in topical over-the-counter products for temporary management of mild to moderate muscular and joint pains.

    Mixtures: Arthritis Extra Strength Roll-ON LotionCategories: Non COX-2 selective NSAIDS, Anti-Inflammatory Agents, Non-Steroidal (Non-Selective)
  2. Drug

    Ketotifen

    go.drugbank.com/drugs/DB00920
    ApprovedInvestigational

    [A231204] In the US, it is now used in an over-the-counter ophthalmic formulation for the treatment of itchy eyes associated with allergies,[L32278] and in Canada a prescription-only oral formulation is … [A231204] Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis.

    Categories: Heterocyclic Compounds, 1-RingProducts: Itchy Eye Original Prescription Strength, Allergy Eye Original Prescription Strength
  3. Drug

    Naphazoline

    go.drugbank.com/drugs/DB06711
    Approved

    It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807]. … Naphazoline was first developed in 1942 as a nasal formulation for congestion[A176609].

    Mixtures: OSMOCROM-N ®, Clear Eyes Acr By MurineCategories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-1 Receptor Agonists
  4. Indication

    Mucopolysaccharidosis Type I (MPS I)

    go.drugbank.com/conditions/DBCOND0065667
    Drugs: Laronidase
    Synonyms: Mucopolysaccharidosis Type I (MPS I), MPS I H
  5. Drug

    Guaifenesin

    go.drugbank.com/drugs/DB00874
    ApprovedInvestigationalVet approved

    Guaifenesin possesses a storied history, having been originally formally approved by the US FDA in 1952 and continues to be one of very few - if not perhaps the only drug that is readily available and … Since that time the agent has been a combination component of various prescription and non-prescription over-the-counter cough and cold products and is currently a widely available over-the-counter generic

    Mixtures: UBAT BATUK KANAK-KANAK CAP KAKI TIGA, Triaminic Decongest+expect Liqui-gels CapInternational brands: Duratuss G
  6. Drug

    Lidocaine

    go.drugbank.com/drugs/DB00281
    ApprovedInvestigationalVet approved

    Regardless, lidocaine is currently available as a relatively non-expensive generic medication that is written for in millions of prescriptions internationally on a yearly basis. … In doing so, however, it can block or decrease muscle contractile, resulting in effects like vasodilation, hypotension, and irregular heart rate, among others [F4349, L5930, L5948].

    Synonyms: 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide, 2-(Diethylamino)-2',6'-acetoxylidideInternational brands: L-Caine, Lidoject-1
  7. Drug

    Ctenocephalides felis

    go.drugbank.com/drugs/DB10693
    Approved

    Cat flea allergenic extract is used in allergenic testing.

    Synonyms: cat flea allergenic extractCategories: Non-Standardized Insect Allergenic Extract
  8. Drug

    Docusate

    go.drugbank.com/drugs/DB11089
    ApprovedInvestigational

    Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass [L1801]. Docusate can be orally or rectally administered. … Recently there has been pressure to stop prescribing docusate as it has been identified as an ineffective medicine[A176972,A176987,L5912].

    Mixtures: Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA, Regulex D CapProducts: Up and up stool softener, Doxate-C Cap 240mg USP
  9. Drug

    Piperazine

    go.drugbank.com/drugs/DB00592
    ApprovedVet approvedWithdrawn

    Outside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate, but in clinical experience it has not proved equally successful. … Piperazine compounds mediate their anthelmintic action by generally paralyzing parasites, allowing the host body to easily remove or expel the invading organism.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: NEO ULTRAXON, OBAT CACING U3
  10. Target

    Signal peptidase I

    go.drugbank.com/bio_entities/BE0001322
    TargetEscherichia coli (strain K12)

    Polypeptides: Signal peptidase ISynonyms: SPase I, Leader peptidase I