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Displaying results 161 - 170 of 624 in total
  1. Target

    Cytochrome b-c1 complex subunit 10

    go.drugbank.com/bio_entities/BE0003859
    TargetHumans

    The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.

    Polypeptides: Cytochrome b-c1 complex subunit 10Synonyms: Complex III subunit 10, Complex III subunit XI
  2. Target

    Cytochrome b-c1 complex subunit 7

    go.drugbank.com/bio_entities/BE0003860
    TargetHumans

    The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.

    Polypeptides: Cytochrome b-c1 complex subunit 7Synonyms: Complex III subunit 7, Complex III subunit VII
  3. Target

    Cytochrome b6-f complex subunit 6

    go.drugbank.com/bio_entities/BE0003907
    TargetMastigocladus laminosus

    PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex. … Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (PubMed:14526088

    Polypeptides: Cytochrome b6-f complex subunit 6Synonyms: Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI
  4. Target

    Trafficking protein particle complex subunit 6B

    go.drugbank.com/bio_entities/BE0004276
    TargetHumans

    Component of a transport protein particle (TRAPP) complex that may function in specific stages of inter-organelle traffic (PubMed:16025134, PubMed:16828797).

    Polypeptides: Trafficking protein particle complex subunit 6BSynonyms: TRAPP complex subunit 6B
  5. Target

    KAT8 regulatory NSL complex subunit 3

    go.drugbank.com/bio_entities/BE0009091
    TargetHumans

    Non-catalytic component of the NSL histone acetyltransferase complex, a multiprotein complex that mediates histone H4 acetylation at 'Lys-5'- and 'Lys-8' (H4K5ac and H4K8ac) at transcription start sites … The NSL complex also acts as a regulator of gene expression in mitochondria (PubMed:27768893).

    Polypeptides: KAT8 regulatory NSL complex subunit 3Synonyms: NSL complex protein NSL3
  6. Drug

    Pixantrone

    go.drugbank.com/drugs/DB06193
    ApprovedWithdrawn

    It will compare pixantrone efficacy to that of gemcitabine. [2]

  7. Indication

    Uncomplicated Urinary Tract Infections caused by Citrobacter freundii complex

    go.drugbank.com/conditions/DBCOND0173161
    Drugs: Gepotidacin
    Synonyms: Uncomplicated Urinary Tract Infections caused by Citrobacter freundii complex
  8. Drug

    Unoprostone

    go.drugbank.com/drugs/DB06826
    ApprovedWithdrawn

    The main indication of Unoprostane is treatment of glucoma.

  9. Drug

    Choline C 11

    go.drugbank.com/drugs/DB09277
    Approved

    Choline C 11 is a marker for cellular proliferation as its main molecule is a precursor for the biosynthesis of phospholipids which are essential components of all cell membranes.

  10. Drug

    Migalastat

    go.drugbank.com/drugs/DB05018
    ApprovedInvestigational

    Fabry disease is a rare, progressive genetic disorder characterized by a defective GLA gene that causes a deficiency in the enzyme alpha-Galactosidase A (alpha-Gal A). This enzyme is responsible for breaking down glycosphingolipid substr...