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Larotrectinib
go.drugbank.com/drugs/DB14723ApprovedInvestigational[L49821] Larotrectinib was granted accelerated approval by the FDA in November 2018 for the treatment of Trk-positive solid tumors. … It was notable for being the second tissue-agnostic chemotherapy ever approved by the FDA.[L4847]. On April 10, 2025, the FDA granted full drug approval.[L52805]
Products: VITRAKVI®CÁPSULAS DE 100MG, VITRAKVI HARD CAPSULE 100MGCyanocobalamin
go.drugbank.com/drugs/DB00115ApprovedInvestigationalNutraceuticalThis drug was initially approved by the FDA in 1942 [FDA label]. … Vitamin B12 has many forms, including the cyano-, methyl-, deoxyadenosyl- and hydroxy-cobalamin forms.
Mixtures: Prim - Royal P.M.T., Bal-Care DHAProducts: Vitamin B12 100mcg, Vitamin B12 Tab 100mcgTestosterone cypionate
go.drugbank.com/drugs/DB13943ApprovedInvestigationalIt was developed by the company Pharmacia and Upjohn and FDA approved on July 25, 1979.
Products: .- Im 100mg/ml, Depo-testosterone Inj 100mg/mlSitagliptin
go.drugbank.com/drugs/DB01261ApprovedInvestigationalSitagliptin was granted FDA approval on October 16, 2006[L6061].
Mixtures: JANUMET XR TABLET 100MG/1000MG, Tablet 50mg/1000mgProducts: JANUVIA® 100MG, hovid-Sitagliptin Tablet 100mgCitric acid
go.drugbank.com/drugs/DB04272ApprovedInvestigationalNutraceuticalVet approvedThe salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. … Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020.
Mixtures: Teruflex Blood Bag System With Diversion Blood Sampling Arm 70 Ml Cpda-1, TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose Adenine (CPDA-1)Products: bdr Re-action natural low base skin refiner exfoliation essenceRemdesivir
go.drugbank.com/drugs/DB14761ApprovedInvestigational[A191427, A198810] Remdesivir was confirmed as a non-obligate chain terminator of RdRp from SARS-CoV-2 and the related SARS-CoV and MERS-CoV,[A222398] and has been investigated in multiple COVID-19 clinical … [A222393] Remdesivir activity against the _Coronaviridae_ family was first demonstrated in 2017,[A191382] leading to considerable interest in remdesivir as a possible treatment for COVID-19.
Products: COVIFOR (REMDESIVIR FOR INJECTION 100MG/VIAL), VEKLURY® LYOPHILIZED POWDER FOR IV INFUSION 100MG/VIALGuselkumab
go.drugbank.com/drugs/DB11834ApprovedInvestigationalDeveloped by Janssen, the subcutenous injection form of guselkumab was approved in July 2017 under the market name Tremfya for the treatment of adult patients with moderate-to-severe plaque psoriasis.
Products: TREMFYA 100MG/ML SOLUTION FOR INJECTION, Tremfya One-Press 100mg/ml Solution for InjectionSildenafil
go.drugbank.com/drugs/DB00203ApprovedInvestigationalAlthough the medication has historically been most popularly recognized as Pfizer's brand name Viagra, sildenafil is currently available generically and even as a non-prescription over the counter medication … Interestingly enough, it is precisely via this mechanism why sildenafil was at first researched as a potential treatment for angina - or chest pain associated with inadequate blood flow to the heart -
Products: Avogra 100mg Tablet, Maxefil 100mg TabletDidanosine
go.drugbank.com/drugs/DB00900ApprovedInvestigationalA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. … Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative
Products: Videx Chewable Dispersible Tab 100mg, Videx Chewable Dispersible Tab 150mgFluvoxamine
go.drugbank.com/drugs/DB00176ApprovedInvestigationalFluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised of approximately 35,000 patients. … It was launched in the US in December 1994 and in Japan in June 1999. As of the end of 1995, more than 10 million patients worldwide have been treated with fluvoxamine.
Products: FEVARIN 100MG, Gen-fluvoxamine 100mg