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Ketoconazole
go.drugbank.com/drugs/DB01026ApprovedInvestigational[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus. … Ketoconazole and its predecessor [clotrimazole] continue to be used in topical formulations.
Products: KOFEN, A-BE LOTIONTeprotumumab
go.drugbank.com/drugs/DB06343ApprovedInvestigationalTeprotumumab is a fully human IgG1 monoclonal antibody directed against the human insulin-like growth factor-1 receptor. … approved by the FDA in January 2020 for the treatment of TED.
Categories: Insulin-like Growth Factor-1 Receptor InhibitorSynonyms: Immunoglobulin G1, anti-(human insulin-like growth factor I receptor) (human monoclonal heavy chain), disulfide with human monoclonal light chain, dimerGentamicin
go.drugbank.com/drugs/DB00798ApprovedInvestigationalVet approved[A234349] It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability. … [A234364] This synergistic activity is not only important for the treatment of complex infections, but can also contribute to dose optimization and reduced adverse effects.
Mixtures: FITODERM TC, GENTAMICINA E BETAMETASONE IDIProducts: HOE GENTAMICIN CREAM 0.1% W/W, HOE Gentamicin Cream 0.1% W/WTrimebutine
go.drugbank.com/drugs/DB09089ApprovedInvestigationalIt is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI disorders [A19691]. … It is used to restore normal bowel function and is commonly present in pharmaceutical mixtures as trimebutine maleate salt form.
Products: DEBRUTIN FORT 200 MG TABLET,20 TB, DEBRUTIN FORT 200 MG TABLET,40 TBTrimipramine
go.drugbank.com/drugs/DB00726ApprovedInvestigationalTricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Adrenergic alpha-1 Receptor AntagonistsProducts: TRIMIPRAMIN AL 40MG/ML TRBrimonidine
go.drugbank.com/drugs/DB00484ApprovedInvestigational[A178969] The ophthalmic solution of brimonidine was first approved by the FDA in 1996 as Alphagan [label] and brimonidine is the only selective alpha-adrenergic receptor agonist approved for chronic treatment … [A178951] It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors.
Mixtures: TQ BRIMOLOL® SOLUCION OFTALMICA, BRIMOCHEK -T EYE DROPS SOLUTIONCategories: Adrenergic alpha-2 Receptor AgonistsLB54640
go.drugbank.com/drugs/DB18331InvestigationalLB54640 is orally-administered small molecule agonist of the melanocortin 4 receptor.
Synonyms: Oral melanocortin 4 receptor agonist, Small molecule melanocortin 4 receptor agonistBiotin
go.drugbank.com/drugs/DB00121ApprovedInvestigationalNutraceuticalIt occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Mixtures: Hoa 1, Folika-TProducts: Tk-naxThallous chloride
go.drugbank.com/drugs/DB09316ApprovedWithdrawnIt is created from the treatment of thallium(I) sulfate with hydrochloric acid. This solid crystallizes in the caesium chloride motif. It is used as a diagnostic radiopharmaceutical. … The following are among the possible side effects: Blurred vision, chest pain or discomfort, chills, confusion, cough, difficulty with breathing, difficulty with swallowing, and dizziness.
Products: Thalliumchlorid (201TI) CIS bio international Injektionslösung TL-201-S-1Epidermal Growth Factor Receptor variant III (EGFRvIII) chimeric antigen receptor T cells
go.drugbank.com/drugs/DB18654InvestigationalSynonyms: Epidermal Growth Factor Receptor variant III (EGFRvIII) chimeric antigen receptor T cells, EGFRvIII CAR-T