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Displaying results 161 - 170 of 4235 in total
  1. Drug

    Glycine

    go.drugbank.com/drugs/DB00145
    ApprovedInvestigationalNutraceuticalVet approved

    It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.

  2. Drug

    Tenocyclidine

    go.drugbank.com/drugs/DB01520
    IllicitInvestigational

    Tenocyclidine (TCP, thienyl cyclohexylpiperidine) is a dissociative anesthetic drug with stimulant and hallucinogenic effects. It is more potent than phencyclidine and hence, this drug was classified under the schedule 1 in 1970.

  3. Drug

    Homatropine

    go.drugbank.com/drugs/DB11181
    Approved

    Homatropine hydrobromide has been administered as ophthalmic solutions as a cycloplegic to temporarily paralyze accomodation, and to induce mydriasis (the dilation of the pupil); however such therapeutic … Homatropine is an anticholinergic drug that acts as an antagonist at muscarinic acetylcholine receptors.

  4. Drug

    Pentetic acid

    go.drugbank.com/drugs/DB14007
    ApprovedInvestigational

    [A32501] It is currently considered, in all the dosage forms, as a member of the list of approved inactive ingredients for drug products by the FDA. … [L2242] DPTA was developed by the pharmaceutical company CIS US and FDA approved on April 14, 2004.[L1469]

  5. Drug

    Trolamine

    go.drugbank.com/drugs/DB13747
    ApprovedInvestigational

    It is commonly used as a pH adjuster and surfactant in industrial and cosmetic products such as skin and hair conditioning products. … Trolamine, which is also referred to as triethanolamine (TEA), is a tertiary amine and a triol. It is a bifunctional compound that exhibits both properties of alcohols and amines.

  6. Drug

    Tofersen

    go.drugbank.com/drugs/DB14782
    ApprovedInvestigational

    [L46108] Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more than 200 SOD1 mutations documented. … [A259028,A259033] Tofersen was granted accelerated approval from the FDA on April 25, 2023, as the first treatment for adults with ALS caused by SOD1 mutation.

  7. Drug

    Selenic acid

    go.drugbank.com/drugs/DB11068
    Approved

    It may be found in over-the-counter daily dietary supplements as a source of [DB11135], an essential trace mineral for human health.

  8. Drug

    Chromic chloride

    go.drugbank.com/drugs/DB09129
    Approved

    Chromic chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).

  9. Drug

    Mequinol

    go.drugbank.com/drugs/DB09516
    ApprovedWithdrawn

    It is used as an inhibitor for acrylic monomers and acrylonitirles, as a stabilizer for chlorinated hydrocarbons and ethyl cellulose, as an ultraviolet inhibitor, as a chemical intermediate in the manufacture … It is found as an active ingredient in topical drugs used for skin depigmentation indicated for the treatment of solar lentigines.

  10. Drug

    Technetium Tc-99m mebrofenin

    go.drugbank.com/drugs/DB09137
    ApprovedWithdrawn

    This is possible as Technetium-99m decays by isomeric transition to technetium-99 through the release of a gamma ray. … Liver and gallbladder imaging is enabled through attachment to mebrofenin as this molecule has high hepatic uptake and fast biliary excretion, resulting in improved hepatic imaging.