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Displaying results 1691 - 1700 of 10000 in total
  1. Target

    N-lysine methyltransferase KMT5A

    go.drugbank.com/bio_entities/BE0019990
    TargetHumans

    Nucleosomes are preferred as substrate compared to free histones (PubMed:12086618, PubMed:12121615, PubMed:15200950, PubMed:15933069, PubMed:15933070, PubMed:15964846, PubMed:16517599).

    Synonyms: SET domain-containing protein 8, PR/SET domain-containing protein 07
  2. Drug

    Aspergillus niger var. niger

    go.drugbank.com/drugs/DB10426
    Approved

    Aspergillus niger var. niger is a fungus which can provoke allergic reactions. Aspergillus niger var. niger extract is used in allergenic testing.

    Mixtures: Treatment Set TS333938
  3. Drug

    Zenocutuzumab

    go.drugbank.com/drugs/DB15559
    ApprovedInvestigational

    [L51983] In May 2026, zenocutuzumab was granted additional approval by the US FDA for use in NRG1-positive cholangiocarcinoma. … [L56179] This approval was expedited following receipt of an FDA Commissioner’s National Priority Voucher.

  4. Drug

    Degarelix

    go.drugbank.com/drugs/DB06699
    ApprovedInvestigational

    Degarelix is used for the treatment of advanced prostate cancer. … Reduction in testosterone is important in treating men with advanced prostate cancer.

  5. Drug

    Carprofen

    go.drugbank.com/drugs/DB00821
    ApprovedVet approvedWithdrawn

    Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. … It is no longer marketed for human usage, after being withdrawn on commercial grounds.

  6. Drug

    Omadacycline

    go.drugbank.com/drugs/DB12455
    ApprovedInvestigational

    well-known tetracycline family, and has been shown to be highly effective in animal models at treating increasingly problematic, clinically prevalent infections caused by gram-positive bacteria, such as … methicillin-resistant Staphylococcus aureus (MRSA), and by gram-negative, atypical and anaerobic bacteria, including those resistant to currently available classes of antibiotics and known to cause diseases such as

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  7. Drug

    Acyclovir

    go.drugbank.com/drugs/DB00787
    ApprovedInvestigational

    [L7303,L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old. … Acyclovir is a deoxynucleoside analog antiviral used to treat herpes simplex, _Varicella zoster_, herpes zoster, herpes labialis, and acute herpetic keratitis.

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseProducts: AVIREX-U, ACYCLIN S/CREMA TB X 5 Y 15 G
  8. Drug

    Tamsulosin

    go.drugbank.com/drugs/DB00706
    ApprovedInvestigational

    [Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy. … Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common.

    Mixtures: Aglandin comp. 0,5 mg/0,4 mg-Hartkapseln, Dutaglandin comp. 0,5 mg/0,4 mg-HartkapselnCategories: Genito Urinary System and Sex Hormones
  9. Drug

    Zidebactam

    go.drugbank.com/drugs/DB13090
    Approved

    Zidebactam is a diazabicyclooctane that acts both as a beta-lactamase inhibitor and as an antibacterial in its own right, selectively binding penicillin-binding protein 2. … [L63350] It is available only in fixed combination with [cefepime], which binds PBP3 and PBP1a/b.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  10. Drug

    Polythiazide

    go.drugbank.com/drugs/DB01324
    Approved

    A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)

    Categories: Genito Urinary System and Sex Hormones