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Vorinostat
go.drugbank.com/drugs/DB02546ApprovedInvestigationalIt is the first in a new class of agents known as histone deacetylase inhibitors. … A recent study suggested that vorinostat also possesses some activity against recurrent glioblastoma multiforme, resulting in a median overall survival of 5.7 months (compared to 4 - 4.4 months in earlier
Products: ZOLINZA®VORINOSTAT 100 MG CAPSULASMitogen-activated protein kinase kinase kinase 10
go.drugbank.com/bio_entities/BE0009462TargetHumansActivates the JUN N-terminal pathway
Polypeptides: Mitogen-activated protein kinase kinase kinase 10Tumor necrosis factor ligand superfamily member 10
go.drugbank.com/bio_entities/BE0010497TargetHumansCytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG (PubMed:10549288, PubMed:26457518). Induces apoptosis. Its activity may be modulated by binding to the d...
Polypeptides: Tumor necrosis factor ligand superfamily member 10Ixazomib
go.drugbank.com/drugs/DB09570ApprovedInvestigational[A264329] Ixazomib was approved by the FDA on November 20, 2015, making it the first oral proteasome inhibitor approved in the US. … [A264319] It was later approved by Health Canada on August 3, 2016,[L51239] and by the EMA on November 21, 2016.
Synonyms: 2-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-5-oxo-1,3,2-dioxaborolane-4,4-diacetic acid, BORONIC ACID, B-((1R)-1-((2-((2,5-DICHLOROBENZOYL)AMINO)ACETYL)AMINO)-3-METHYLBUTYL)-Products: NİNLARO 2.3 MG MG KAPSÜL, 3 ADET, NINLARO® 3.0 MGClevidipine
go.drugbank.com/drugs/DB04920ApprovedInvestigationalClevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not an option.
Categories: Heterocyclic Compounds, 1-RingProducts: Cleviprex 0,5 mg/ml Emulsion zur InjektionNicotinamide
go.drugbank.com/drugs/DB02701ApprovedInvestigationalAn important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. … Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Mixtures: Cellmov Cell Line Mask, COMPLEJO B X 10 ML SOLUCION INYECTABLECategories: Heterocyclic Compounds, 1-RingRitodrine
go.drugbank.com/drugs/DB00867ApprovedWithdrawnAdrenergic beta-agonist used to control premature labor.
Synonyms: p-Hydroxy-alpha-(1-((p-hydroxyphenethyl)amino)ethyl)benzyl alcoholCategories: Adrenergic beta-2 Receptor AgonistsRebamipide
go.drugbank.com/drugs/DB11656ApprovedInvestigationalRebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and Gastric Adenoma and Early Gastric Cancer.
Categories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household settingProducts: MUCOSTA TABLETS 100 MG, บาปิด 100Disintegrin and metalloproteinase domain-containing protein 10
go.drugbank.com/bio_entities/BE0002404TargetHumansTransmembrane metalloprotease which mediates the ectodomain shedding of a myriad of transmembrane proteins, including adhesion proteins, growth factor precursors and cytokines being essential for development and tissue homeostasis (PubMe...
Polypeptides: Disintegrin and metalloproteinase domain-containing protein 10Synonyms: ADAM 10Sialic acid-binding Ig-like lectin 10
go.drugbank.com/bio_entities/BE0018431TargetHumansPutative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid (By similarity). The sialic acid recognition site may be masked by cis interactions with ...
Polypeptides: Sialic acid-binding Ig-like lectin 10Synonyms: Siglec-10