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Dactinomycin
go.drugbank.com/drugs/DB00970ApprovedInvestigationalAs a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)
Synonyms: 2-amino-N,N'-bis(hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo(2,1-i)(1,4,7,10,13)oxatetra-azacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide, 3H-PHENOXAZINE-1,9-DICARBOXAMIDE, 2-AMINO-N,N'-BIS(HEXADECAHYDRO-6,13-DIISOPROPYL-2,5,9-TRIMETHYL-1,4,7,11,14-PENTAOXO-1H-PYRROLO(2,1-I)(1,4,7,10,13)OXATETRAAZACYCLOHEXADECIN-10-YL)-4,6-DIMETHYL-3-OXO-Products: DACTINOMYCIN FOR INJECTION 0.5 mg/vialFosamprenavir
go.drugbank.com/drugs/DB01319ApprovedInvestigationalFosamprenavir is a prodrug of amprenavir, an inhibitor of human immunodeficiency virus (HIV) protease.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: TELZIR 700 MG FİLM KAPLI TABLET, 60 ADETIocetamic acid
go.drugbank.com/drugs/DB09403ApprovedIocetamic acid is a diagnostic aid (radiopaque medium)
Products: CHOLEBRINE 750 MG (MEDIO DE CONTRASTE RADIOLOGICO)Manganese cation
go.drugbank.com/drugs/DB06757ApprovedInvestigationalNutraceuticalManganese is a transition metal that was first described in the 19th and 20th centuries. … [A263657, A263667] Manganese intake primarily occurs through the diet,[A263687] as it is found at low levels in many food sources and water.
Mixtures: TRACUTIL® 10 ML AMPOLLAS, Prim - Royal P.M.T.Products: Micro Mn, Ostrophin Pmg Tab 4mgCarbopol 974P
go.drugbank.com/drugs/DB05384ApprovedWithdrawnThe compound, known as BufferGel, was in advanced clinical trials for its ability to prevent pregnancy, but was discontinued. … It was under development by ReProtect LLC. It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted pregnancies.
Products: SICCAFLUID® 2.5 MG/G GEL OFTALMICO, LIQUIGEL UD 2.5MG/G EINZELEchinacea
go.drugbank.com/drugs/DB14240ApprovedCategories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersProducts: Echinacea 500mg 50% Echinacea Angustifolia Root 50% Echinacea Purpurea RootPenbutolol
go.drugbank.com/drugs/DB01359ApprovedInvestigationalWithdrawnPenbutolol also demonstrates high binding affinity to the 5-hydroxytryptamine receptor 1A with antagonistic effects. … Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric drug.
Categories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT1A Receptor AntagonistsProducts: BETAPRESSİN 40 MG FİLM TABLET, 30 TABLETLynestrenol
go.drugbank.com/drugs/DB12474ApprovedWithdrawnLynestrenol is a progestin and prodrug of norethisterone.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ORGAMETRİL 5 MG TABLET, 30 ADETVindesine
go.drugbank.com/drugs/DB00309ApprovedInvestigationalWithdrawnVinblastine derivative with antineoplastic activity against cancer. Major side effects are myelosuppression and neurotoxicity. Vindesine is used extensively in chemotherapy protocols (antineoplastic combined chemotherapy protocols).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Eldisin 5 mg Trockenstechampulle, Eldisine Inj 5mg/2mlHydrocortisone acetate
go.drugbank.com/drugs/DB14539ApprovedInvestigationalVet approvedMixtures: KORTOS 27 MG/5 MG SUPOZİTUVAR, 10 ADET, UREACORT YAĞLI %0,5 + %10 KREM (30 G)Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Inducers