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Displaying results 1711 - 1720 of 1993 in total
  1. Target

    Dual specificity mitogen-activated protein kinase kinase 2

    go.drugbank.com/bio_entities/BE0004744
    TargetHumans

    Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity). Activates BRAF in a KSR1 or KSR2-dependent manner;...

    Synonyms: MEK 2
  2. Drug

    Belzutifan

    go.drugbank.com/drugs/DB15463
    ApprovedInvestigational

    This discovery led to the initial development of belzutifan (at the time called PT2977), which was further developed by a spin-off company named Peloton Pharmaceuticals (which itself was eventually acquired

  3. Drug

    Coal tar

    go.drugbank.com/drugs/DB11082
    Approved

    Coal tar is a brown or black liquid of extremely high viscosity. Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas. Coal tars are complex and variable mixtures of phenols, polycyclic arom...

    Mixtures: Medi-dan Shampoo
  4. Target

    Macrophage metalloelastase

    go.drugbank.com/bio_entities/BE0001198
    TargetEnzymeHumans

    May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 sit...

    Synonyms: ME
  5. Drug

    Furazolidone

    go.drugbank.com/drugs/DB00614
    InvestigationalVet approved

    (From Martindale, The Extra Pharmacopoeia, 30th ed, p514)

  6. Drug

    Astaxanthin

    go.drugbank.com/drugs/DB06543
    Investigational

    It is found in the majority of aquatic organisms with red pigment. Astaxanthin has shown to mediate anti-oxidant and anti-inflammatory actions.

  7. Drug

    Monlunabant

    go.drugbank.com/drugs/DB21537
    Investigational

    investigation in clinical trial NCT06542536 (A Research Study Investigating Safety and Concentration in the Blood After One Dose Tablet of the New Medicine Monlunabant in Healthy Weight Japanese and Caucasian Men … The usage of the INN stem '-nabant' in the name indicates that Monlunabant is a cannabinoid receptor antagonist.

  8. Drug

    Cyd dengue virus serotype 1 live (attenuated) antigen

    go.drugbank.com/drugs/DB15521
    ApprovedInvestigationalWithdrawn

    Mixtures: DENGVAXIA MD, POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION
  9. Drug

    Cyd dengue virus serotype 2 live (attenuated) antigen

    go.drugbank.com/drugs/DB15522
    ApprovedInvestigationalWithdrawn

    Mixtures: DENGVAXIA MD, POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION
  10. Target

    L-selectin

    go.drugbank.com/bio_entities/BE0010361
    TargetHumans

    Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells (PubMed:12403782, PubMed:28011641, PubMed:28489325). Mediates the adherence of lymphocytes to endothelial cells of high endothelial ven...

    Synonyms: gp90-MEL, Lymph node homing receptor