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Dosulepin
go.drugbank.com/drugs/DB09167ApprovedInvestigationalDosulepin (INN, BAN) formerly known as dothiepin (USAN), is a tricyclic antidepressant with anxiolytic properties that is used in several European and South Asian countries, as well as Australia, South … It is not FDA-approved due to low therpeutic index and significant toxicity in overdose.
Categories: Serotonin Receptor Antagonists, Serotonin 5-HT1 Receptor AntagonistsVidPrevtyn Beta
go.drugbank.com/drugs/DB16427Approved[L49691] It comprises a recombinant SARS-CoV-2 spike protein (B.1.351 strain) - produced by recombinant DNA technology using a baculovirus expression system in an insect cell line that is derived from … VidPrevtyn Beta is an adjuvanted, recombinant COVID-19 vaccine developed collaboratively by GlaxoSmithKline (GSK) and Sanofi Pasteur.
Pegulicianine
go.drugbank.com/drugs/DB18731ApprovedInvestigationalPegulicianine is an optical imaging agent indicated for fluorescence imaging in patients with breast cancer. … [L50537] The _in vivo_ enzymatic cleavage of pegulicianine results in two optically active fragments that emit a fluorescent signal that can be detected using a fluorescence imaging device.
Categories: Compounds used in a research, industrial, or household settingTyrothricin
go.drugbank.com/drugs/DB13503ApprovedWithdrawnand 40% neutral linear gramicidins (where valine-gramicidin A is often the major gramicidin present, although the mixture composition can vary) [L4019, L4021, L4022]. … Tyrothricin is an antibiotic peptide complex produced and extracted from the aerobic Gram-positive bacillus Brevibacillus parabrevis [L4019, L4021, A32851] which was previously categorized as Bacillus
Endothelin receptor type B
go.drugbank.com/bio_entities/BE0000043TargetHumansNon-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system
Polypeptides: Endothelin receptor type BSynonyms: Endothelin receptor non-selective typeMuscarinic acetylcholine receptor M3
go.drugbank.com/bio_entities/BE0000045TargetHumansThe muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action
Polypeptides: Muscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor M1
go.drugbank.com/bio_entities/BE0000092TargetHumansThe muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action
Polypeptides: Muscarinic acetylcholine receptor M1Function: G protein-coupled acetylcholine receptor activityCysteinyl leukotriene receptor 2
go.drugbank.com/bio_entities/BE0000099TargetHumansReceptor for cysteinyl leukotrienes. The response is mediated via a G protein that activates a phosphatidylinositol-calcium second messenger system.
Polypeptides: Cysteinyl leukotriene receptor 2Synonyms: G protein-coupled receptor HG57, G protein-coupled receptor GPCR21Lutropin-choriogonadotropic hormone receptor
go.drugbank.com/bio_entities/BE0000134TargetHumansReceptor for lutropin-choriogonadotropic hormone (PubMed:11847099). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:11847099)
Polypeptides: Lutropin-choriogonadotropic hormone receptorSynonyms: Luteinizing hormone receptorRetinoic acid receptor gamma
go.drugbank.com/bio_entities/BE0000144TargetHumansReceptor for retinoic acid.
Polypeptides: Retinoic acid receptor gammaSynonyms: Nuclear receptor subfamily 1 group B member 3