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Carbazochrome
go.drugbank.com/drugs/DB09012ApprovedWithdrawnCarbazochrome has been investigated for use in the treatment of non-surgical acute uncomplicated hemorrhoids in a mixture with [DB13124], and this combination therapy demonstrated efficacy and safe tolerability … It is not FDA-approved but is available as tablets or IM/SC injections in the treatment of hemorrhages in a number of countries.
International brands: Hemosin K, Ophthalm KFavipiravir
go.drugbank.com/drugs/DB12466ApprovedInvestigational[A191688,A191772,A191775] Not only does favipiravir inhibit replication of influenza A and B, but the drug has shown promise in the treatment of avian influenza, and may be an alternative option for … Discovered by Toyama Chemical Co., Ltd. in Japan, favipiravir is a modified pyrazine analog that was initially approved for therapeutic use in resistant cases of influenza.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseEstradiol acetate
go.drugbank.com/drugs/DB13952ApprovedVet approvedEstradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. … Thus, estrone and the sulfate conjugated form, estrone sulfate, are the most abundant circulating estrogens in postmenopausal women [FDA Label].
Icatibant
go.drugbank.com/drugs/DB06196ApprovedInvestigational[A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a treatment for hereditary angioedema. … relief was observed to be 8 hours compared to 36 hours for the placebo treatment.
Magnesium silicate
go.drugbank.com/drugs/DB13249ApprovedWithdrawnIt is the magnesium salt of silicic acid containing an unspecified amount of water. The molecular formula can be expressed more clearly as MgSiO3.xH2O. … [L2603] Under the FDA, magnesium silicate is determined as a member of the substances generally recognized as safe (GRAS) to be used as an anticaking agent.[L2605]
Categories: Drugs for Acid Related DisordersEquine Botulinum Neurotoxin A Immune FAB2
go.drugbank.com/drugs/DB13900ApprovedIt is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes A in adults and pediatric patients. … Equine Botulinum Neurotoxin A Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype A.
Floxuridine
go.drugbank.com/drugs/DB00322ApprovedInvestigationalAn antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection. Floxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution. … It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Efavirenz
go.drugbank.com/drugs/DB00625ApprovedInvestigationala high risk for HIV transmission. … For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with zidovudine or tenofovir is the preferred NNRTI-based regimen.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseProducts: EFAVAX ® TABLETAS RECUBIERTAS POR 600MGPalbociclib
go.drugbank.com/drugs/DB09073ApprovedInvestigational[L5867] It was originally FDA approved on March 2015 for the treatment of HR-positive, HER2-negative advanced or metastatic breast cancer and its indications were updated in April 2019 to include male … patients based on findings from postmarketing reports and electronic health records demonstrating safety and clinical efficacy.
Nylidrin
go.drugbank.com/drugs/DB06152ApprovedWithdrawnNylidrin is utilized to treat several disorders that may benefit from increased blood flow (for example, certain mental disorders, blood vessel disease due to diabetes, frostbite, night leg cramps, and … Therefore, the FDA has withdrawn nylidrin from the U.S. market [L2286].