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Displaying results 1731 - 1740 of 3733 in total
  1. Drug

    Clindamycin

    go.drugbank.com/drugs/DB01190
    ApprovedInvestigationalVet approved

    [A190657] Clindamycin is derived from, and has largely replaced, [lincomycin], a naturally occurring lincosamide and the eponymous member of this antibiotic class, due to its improved properties over

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: Clindacin P
  2. Drug

    Prasterone

    go.drugbank.com/drugs/DB01708
    ApprovedInvestigationalNutraceutical

    DHEA and DHEAS are readily available in the United States, where they are marketed as over-the-counter dietary supplements.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  3. Drug

    Tavapadon

    go.drugbank.com/drugs/DB14899
    Investigational

    Tavapadon is under investigation in clinical trial NCT02262767 (A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of PF-06649751 Co-administered With Trimethobenzamide Hydrochloride

    Synonyms: PF-06649751
  4. Target

    Glycine receptors

    go.drugbank.com/bio_entities/BE0009666
    TargetHumans

    Subunit of heteromeric glycine-gated chloride channels (PubMed:14551753, PubMed:23994010, PubMed:25730860, PubMed:37821459). Plays an important role in the down-regulation of neuronal excitability (PubMed:8298642, PubMed:9009272). Contri...

    Synonyms: Glycine receptor 48 kDa subunit, Glycine receptor 58 kDa subunitPolypeptides: Glycine receptor subunit alpha-1, Glycine receptor subunit beta
  5. Drug

    Lotiglipron

    go.drugbank.com/drugs/DB21631
    Investigational

    Lotiglipron is under investigation in clinical trial NCT05579977 (Trial to Learn About the Study Medicine (PF-07081532) and Rybelsus in People With Type 2 Diabetes and Separately PF-07081532 in People … The usage of the INN stem '-glipron' in the name indicates that Lotiglipron is a glucagon-like peptide 1 receptor (GLPIR) agonist.

  6. Drug

    Ginsenoside Rb1

    go.drugbank.com/drugs/DB06749
    ExperimentalNutraceutical

    Recent research shows that Rb1 affects rat embryo development and has teratogenic effects, causing birth defects.

  7. Drug

    Citric acid

    go.drugbank.com/drugs/DB04272
    ApprovedInvestigationalNutraceuticalVet approved

    A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Ph...

    Mixtures: ACD Blood-Pack Units (PL 146 Plastic), CPD/ADSOL Red Cell Preservation Solution System (PL 2209)
  8. Drug

    Caprospinol

    go.drugbank.com/drugs/DB05263
    Experimental

    Caprospinol (SP-233) is the first drug ever to demonstrate the correlation of clearing beta-amyloid from the brain. It also improves the brain histopathology and recovers memory function.

  9. Drug

    Ferrous aspartate

    go.drugbank.com/drugs/DB13220
    Experimental

    The use of ferrous acetate over ferrous sulfate is currently undergoing an investigation by a clinical trial [L5464]. It is also used for dying of fabric or leather and as a wood preservative.

  10. Drug

    PF-04991532

    go.drugbank.com/drugs/DB11765
    Investigational

    PF-04991532 has been used in trials studying the basic science of Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2, and Glucose Metabolism Disorders.