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Amlexanox
go.drugbank.com/drugs/DB01025ApprovedWithdrawnAmlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis.
Categories: Drugs for Obstructive Airway DiseasesTioconazole
go.drugbank.com/drugs/DB01007ApprovedTopical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus".
Categories: Antifungals for Topical Use, Antifungals for Dermatological UseSetmelanotide
go.drugbank.com/drugs/DB11700ApprovedInvestigationalSetmelanotide is the first available treatment for patients with pro-opiomelanocortin, proprotein subilisin/kexin type 1, or leptin deficiencies. … [A224449] Other earlier treatments for these patients included gastric bypass surgery.[A224449] Patients taking setmelanotide experienced an average weight loss of 0.6 kg/week.
Dental Mesenchymal Pulp Stem Cells
go.drugbank.com/drugs/DB15737InvestigationalThese cells have innate neurogenic potential as their origins are traced to the embryonic neural crest; there is potential for these cells to create neurons and glial cells. … In addition, they are able to differentiate into chondrocytes, adipocytes, and odontoblasts under appropriate conditions.
Denileukin diftitox
go.drugbank.com/drugs/DB00004ApprovedInvestigational>387</sub>)-His and the sequence for human interleukin-2 (IL-2; Ala<sub>1</sub>-Thr<sub>133</sub>). … Denileukin diftitox is an IL2-receptor-directed cytotoxin, is a recombinant DNA-derived fusion protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met<sub>1</sub>-Thr<sub
Abacavir
go.drugbank.com/drugs/DB01048ApprovedInvestigationalAbacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclop...
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseCocarboxylase
go.drugbank.com/drugs/DB01987ApprovedInvestigationalThe coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.
Mixtures: CERNEVIT FOR INJECTION, Cernevit, Lyophilisate for ReconstitutionChlorphenoxamine
go.drugbank.com/drugs/DB09007ApprovedWithdrawnIt is an antihistamine and anticholinergic used to treat itching as well as for its antiparkinsonian effect.
Categories: Antihistamines for Topical Use, Antihistamines for Systemic UseBimatoprost
go.drugbank.com/drugs/DB00905ApprovedInvestigational[L6910] It was initially approved by the FDA in 2001 for ocular hypertension and later approved for hypothrichosis in 2008, as eyelash growth became a desirable adverse effect for patients using this drug … Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form.
Ergoloid mesylate
go.drugbank.com/drugs/DB01049Approved[A32912] All these components are produced by the fungus _Claviceps purpurea_ and are all derivatives of the tetracyclic compound 6-methylergonovine.
Categories: Heterocyclic Compounds with 4 or More Rings