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Displaying results 1741 - 1750 of 7181 in total
  1. Drug

    Secretin human

    go.drugbank.com/drugs/DB09532
    ApprovedInvestigational

    The hormone is produced from the enterochromaffin cells in the duodenum in response to the duodenal content with the pH less than 4.5 [L1875]. … The main action of secretin is to stimulate the pancreas to secrete pancreatic juice for pH regulation in the small intestines.

  2. Drug

    Busulfan

    go.drugbank.com/drugs/DB01008
    ApprovedInvestigational

    It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought about. … According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen.

  3. Drug

    Poloxamer 188

    go.drugbank.com/drugs/DB11333
    Approved

    P188 was originally approved by the FDA in the 1960s as a therapeutic agent to reduce viscosity in the blood before transfusions, however it is no longer available in any approved products [A27217]. … Composed of two hydrophilic side-chains attached to a hydrophobic center core [A27218], its average molecular weight is 8400 Daltons.

  4. Indication

    Alveolitis, Extrinsic Allergic

    go.drugbank.com/conditions/DBCOND0115831
    Drugs: Prednisolone · Prednisone
    Synonyms: Hypersensitivity pneumonitis due to unspecified organic dust
  5. Indication

    Myelofibroses

    go.drugbank.com/conditions/DBCOND0092673
    Drugs: Fedratinib · Oxymetholone · Ruxolitinib
    Synonyms: Myelofibrosis due to another disorder (disorder)
  6. Indication

    Pneumonia, Pneumocystis Jerovici

    go.drugbank.com/conditions/DBCOND0070467
    Drugs: Atovaquone · Clindamycin · Fluorescein · Pentamidine · Prednisolone · Prednisone +4 more
    Synonyms: Pneumonia due to Pneumocystis carinii
  7. Drug

    Threonine

    go.drugbank.com/drugs/DB00156
    ApprovedInvestigationalNutraceutical

    An essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins.

    Mixtures: Vamin N, AMINOSTERIL N-HEPA 8%
  8. Drug

    Triamterene

    go.drugbank.com/drugs/DB00384
    Approved

    [T28] Due to its effects on increased serum potassium levels, triamterene is associated with a risk of producing hyperkalemia. … [A177985] Since it acts on the distal nephron where only a small fraction of sodium ion reabsorption occurs, triamterene is reported to have limited diuretic efficacy.

    Mixtures: Nu-triazide Tab 50 Mg/25 mg
  9. Drug

    Afatinib

    go.drugbank.com/drugs/DB08916
    ApprovedInvestigational

    Gilotrif (afatinib) is the first FDA-approved oncology product from Boehringer Ingelheim [L2939]. … oral use, afatinib tablets are a first-line (initial) treatment for patients with metastatic non-small cell lung cancer (NSCLC) with common epidermal growth factor receptor (EGFR) mutations as detected by

  10. Drug

    Avanafil

    go.drugbank.com/drugs/DB06237
    Approved

    In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both [sildenafil] and [vardenafil] but less selectivity than [tadalafil], suggesting a relatively

    Synonyms: (S)-4-(3-Chloro-4-methoxybenzylamino)-2-(2-hydroxymethylpyrrolidin-1-yl)-N-pyrimidin-2-ylmethyl-5-pyrimidinecarboxamide