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Displaying results 1741 - 1750 of 10000 in total
  1. Drug

    Thiopental

    go.drugbank.com/drugs/DB00599
    ApprovedInvestigationalVet approvedWithdrawn

    (From Martindale, The Extra Pharmacopoeia, 30th ed, p920) … It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: 2-Thio-5-ethyl-5-sec-pentylbarbituric acid, 5-Ethyl-5-(1-methyl-butyl)-2-thioxo-dihydro-pyrimidine-4,6-dione
  2. Drug

    Mucopolysaccharide polysulphate

    go.drugbank.com/drugs/DB16564
    Investigational

    Products: HIRUDOID GEL 300 mg/100 g, Forte Cream 445 mg/ 100g
  3. Drug

    Bezafibrate

    go.drugbank.com/drugs/DB01393
    ApprovedInvestigational

    It decreases low density lipoproteins and increases high density lipoproteins.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsSynonyms: 2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid
  4. Drug

    Carbimazole

    go.drugbank.com/drugs/DB00389
    Approved

    An imidazole antithyroid agent. Carbimazole is metabolized to methimazole, which is responsible for the antithyroid activity.

    Synonyms: Ethyl 3-methyl-2-thioimidazoline-1-carboxylateProducts: CARBIMAZOLE 5 TABLET 5 mg, CAMAZOL TABLET 5 mg
  5. Drug

    Liotrix

    go.drugbank.com/drugs/DB01583
    Approved

    It is now known that the thyroid gland secretes approximately ten times more T4 than T3 and that 80% of serum T3 is derived from deiodination of T4 in peripheral tissues. … It consists of levothyroxine sodium (thyroxine, T4) and liothyronine sodium (triiodothyronine, T3) in a 4 to 1 ratio by weight.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsSynonyms: Liotrix (T4;T3)
  6. Drug

    Triclosan

    go.drugbank.com/drugs/DB08604
    Approved

    An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. … It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards

    Mixtures: PREVENT 2 EN 1, TALCO MEDICADO T 24Synonyms: 5-Chloro-2-(2,4-dichloro-phenoxy)-phenol, 2,4,4'-Trichloro-2'-hydroxydiphenyl ether
  7. Drug

    Tolfenamic acid

    go.drugbank.com/drugs/DB09216
    Approved

    Tolfenamic acid, with the formula N-(2-methyl-3-chlorphenyl)-anthranilic acid, is a nonsteroidal anti-inflammatory agent. … [A31824] It was discovered by scientists at Medica Pharmaceutical Company in Finland. It is used in the UK as a treatment for migraine under the name of Clotam.

    Categories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesProducts: TOLFEDINE TABLET 60 MG, TOLFEDINE TABLETS 6 MG
  8. Drug

    Carglumic acid

    go.drugbank.com/drugs/DB06775
    ApprovedInvestigational

    Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase. … Food and Drug Administration (FDA) on 18 March 2010.

    Synonyms: (2S)-2-(carbamoylamino)pentanedioic acid, (S)-2-ureidopentanedioic acidProducts: Kargoced 200 mg Dağılabilir Tablet, 14 ADET, PERLUGA 200 MG DAĞILABİLİR TABLET, 5 ADET
  9. Drug

    Gemifloxacin

    go.drugbank.com/drugs/DB01155
    ApprovedInvestigational

    It is available in oral formulations. Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are essential for bacterial growth. … Gemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia.

    Categories: Heterocyclic Compounds, 2-Ring, 4-QuinolonesProducts: ONFACT 320 MG FİLM TABLET, 5 ADET, FACTIVE 320 MG FİLM TABLET, 5 ADET
  10. Drug

    Tyrothricin

    go.drugbank.com/drugs/DB13503
    ApprovedWithdrawn

    Tyrothricin is an antibiotic peptide complex produced and extracted from the aerobic Gram-positive bacillus Brevibacillus parabrevis [L4019, L4021, A32851] which was previously categorized as Bacillus … Nevertheless, as tyrothricin is both cytolytic and hemolytic, it does demonstrate systemic toxicity [L4019, L4021, L4022], although certain formulations that are safe for human use like throat lozenges

    Mixtures: Dorithricin Halstabletten Classic 0,5 mg / 1,0 mg / 1,5 mg Lutschtabletten, Dorithricin Halstabletten Waldbeergeschmack 0,5 mg / 1,0 mg / 1,5 mg LutschtablettenProducts: HYDROTRICINE PASTİL, 24 ADET