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Displaying results 1751 - 1760 of 8411 in total
  1. Drug

    Tolmetin

    go.drugbank.com/drugs/DB00500
    Approved

    A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.

    Synonyms: 1-Methyl-5-p-toluoylpyrrole-2-acetic acid, 5-(p-Toluoyl)-1-methylpyrrole-2-acetic acidInternational brands: Tolectin DS
  2. Drug

    AVR-RD-02

    go.drugbank.com/drugs/DB17650
    Investigational

    AVR-RD-02 is an investigational _ex vivo_ lentiviral gene therapy developed by AVROBIO Inc. … AVR-RD-02 is being investigated in Gaucher Disease.[L45958]

  3. Drug

    Vadadustat

    go.drugbank.com/drugs/DB12255
    ApprovedInvestigational

    [A244165] Vadadustat is an orally administered inhibitor of HIF-PH with a safety and efficacy profile non-inferior to [darbepoetin alfa] for the treatment of anemia in patients with CKD undergoing dialysis … [A244165] A relatively new and alternative treatment option for patients with anemia associated with CKD is the use of small molecule inhibitors of hypoxia-inducible factor prolyl-hydroxylase (HIF-PH

    Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 Enzyme Inducers
  4. Drug

    Acetylcarnitine

    go.drugbank.com/drugs/DB08842
    ApprovedInvestigational

    Acetylcarnitine can be synthesized, but it is also naturally found in adequate amounts in healthy humans. … Acetylcarnitine is an investigational drug in the United states, Italy, United Kingdom, China, Israel, and Norway, and it is approved in Italy, Portugal, Argentina, Chile, Philippines, Australia, and India

  5. Target

    Streptogramin A acetyltransferase

    go.drugbank.com/bio_entities/BE0001238
    TargetEnterococcus faecium

    Inactivates the A compounds of streptogramin antibiotics by acetylation, thus providing resistance to these antibiotics.

    Synonyms: Vat(D)
  6. Target

    Carbonic anhydrase 5A, mitochondrial

    go.drugbank.com/bio_entities/BE0003626
    TargetEnzymeHumans

    Mitochondrial carbonic anhydrase that catalyzes the reversible conversion of carbon dioxide to bicarbonate/HCO3 (PubMed:24530203, PubMed:8356065, PubMed:16807956, PubMed:16686544, PubMed:17127057, PubMed:17314045, PubMed:19186056, PubMed...

    Synonyms: CA-VA, Carbonic anhydrase VA
  7. Drug

    Nabilone

    go.drugbank.com/drugs/DB00486
    ApprovedInvestigational

    Tetrahydrocannabinol (THC) and cannabidiol (CBD) are the two most abundant cannabinoids found naturally in the resin of the marijuana plant, both of which are pharmacologically active due to their interaction … This can be achieved through heating, smoking, vaporization, or baking of dried unfertilized female cannabis flowers.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsProducts: Ran-nabilone
  8. Drug

    Thymidine

    go.drugbank.com/drugs/DB04485
    ApprovedInvestigational

    extensively investigated for nearly a decade as a biochemical modulator to enhance the efficacy and reduce the toxicity of established anti-metabolite chemotherapeutic agents, such as 5-Fluorouracil (FU

    Synonyms: -D-erythro-pentofuranosyl)-5-methyl-, -D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
  9. Drug

    Thiabendazole

    go.drugbank.com/drugs/DB00730
    ApprovedVet approvedWithdrawn

    2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of P...

    Mixtures: DEXORYL EAR DROPS OILY SUSPENSIONCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inhibitors
  10. Drug

    Carindacillin

    go.drugbank.com/drugs/DB09319
    ApprovedWithdrawn

    Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of [carbenicillin] marketed by Pfizer as Geocillin. It is no longer marketed in the United States.