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Displaying results 1751 - 1760 of 1809 in total
  1. Drug

    Rosuvastatin

    go.drugbank.com/drugs/DB01098
    ApprovedInvestigational

    Rosuvastatin is also a unique member of the class of statins due to its high hydrophilicity which increases hepatic uptake at the site of action, low bioavailability, and minimal metabolism via the Cytochrome

  2. Drug

    Pramocaine

    go.drugbank.com/drugs/DB09345
    Approved

    Pramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic. It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect bites, hives/rashes due to poison i...

    Mixtures: Vida Mia Calaclear, Best Choice Anti-Itch ClearProducts: Bikini Zone Medicated After Shave Spray, Bikini Zone MEDICATED After Shave Fresh Scent
  3. Target

    Integrin beta-2

    go.drugbank.com/bio_entities/BE0001041
    TargetHumans

    Integrin ITGAM:ITGB2 is also a receptor for factor X. Integrin ITGAD:ITGB2 is a receptor for ICAM3 and VCAM1 (PubMed:10438935, PubMed:8777714, PubMed:9841932). … Integrin ITGAM:ITGB2/MAC-1 complex functions as a signaling receptor for the ligand receptor ICAM1, ensuring adhesion between stimulated neutrophils and stimulated endothelial cells (PubMed:1980124).

    Synonyms: Complement receptor C3 subunit beta
  4. Target

    Sialic acid-binding Ig-like lectin 7

    go.drugbank.com/bio_entities/BE0001648
    TargetHumans

    In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through

    Synonyms: Adhesion inhibitory receptor molecule 1
  5. Target

    GTP-binding nuclear protein Ran

    go.drugbank.com/bio_entities/BE0004559
    TargetHumans

    GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs (PubMed:10400640, PubMed:17209048, PubMed:26272610, PubMed:27306458, PubMed:8276887, PubMed:8636225, Pu...

    Synonyms: Androgen receptor-associated protein 24
  6. Drug

    Doxofylline

    go.drugbank.com/drugs/DB09273
    Investigational

    Decreased affinity for adenosine receptors may account for the better safety profile of doxofylline compared to theophylline [L1169].

    Categories: Adrenergic beta-2 Receptor Agonists
  7. Drug

    Duloxetine

    go.drugbank.com/drugs/DB00476
    ApprovedInvestigational

    Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymb...

  8. Target

    Large ribosomal subunit protein uL16

    go.drugbank.com/bio_entities/BE0009104
    TargetHumans

    Component of the large ribosomal subunit (PubMed:26290468). Plays a role in the formation of actively translating ribosomes (PubMed:26290468). May play a role in the embryonic brain development (PubMed:25316788)

    Synonyms: Laminin receptor homolog
  9. Target

    Integrin alpha-2

    go.drugbank.com/bio_entities/BE0012664
    TargetHumans

    Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen.

    Synonyms: Collagen receptor
  10. Drug

    Avobenzone

    go.drugbank.com/drugs/DB09495
    ApprovedInvestigational

    Avobenzone is dibenzoyl methane derivative. It is oil soluble ingredient. Avobenzone has the ability to absorb ultraviolet light over wider range of wavelengths. It is included in many commercially available sunscreens which are used as ...

    Mixtures: Kara Vita SPF 29, UV Capture Vita Sun Gel