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Displaying results 1751 - 1760 of 10000 in total
  1. Drug

    Butenafine

    go.drugbank.com/drugs/DB01091
    Approved

    Butenafine's mechanism of action is believed to involve the synthesis inhibition of sterols. … In particular, butenafine acts to inhibit the activity of the squalene epoxidase enzyme that is essential in the formation of sterols necessary for fungal cell membranes.

    Products: BUTAFLY % 1 LOSYON ,10 ML, BUTEFIN %1 KREM, 30 G
  2. Drug

    Asenapine

    go.drugbank.com/drugs/DB06216
    ApprovedInvestigational

    Asenapine also belongs to the dibenzo-oxepino pyrrole class. It is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use. FDA approved on August 13, 2009. … Developed by Schering-Plough after its merger with Organon International, asenapine is a sublingually administered, atypical antipsychotic for treatment of schizophrenia and acute mania associated with

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin 5-HT1 Receptor AntagonistsProducts: SYCREST 5MG DILALTI TABLET, 100 TABLET, SYCREST 10MG DILALTI TABLET, 100 TABLET
  3. Drug

    Lapatinib

    go.drugbank.com/drugs/DB01259
    ApprovedInvestigational

    It binds to the intracellular phosphorylation domain to prevent receptor autophosphorylation upon ligand binding. … Lapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and lung cancer.

    Synonyms: N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 Substrates
  4. Drug

    Sulfinpyrazone

    go.drugbank.com/drugs/DB01138
    Approved

    A uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.

    Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesProducts: ยาเม็ดซัลฟิน 100 มิลลิกรัม, Sulfinpyrazone 100 Tab
  5. Drug

    Clove

    go.drugbank.com/drugs/DB10672
    Approved

    Clove allergenic extract is used in allergenic testing.

    Synonyms: Ding xiang bud, Clove bud extract
  6. Drug

    Dichloroacetic acid

    go.drugbank.com/drugs/DB08809
    ApprovedInvestigationalWithdrawn

    A phase 1 study in 5 patients concluded that DCA was safe, but wasn't designed to establish effectiveness. … Dichloroacetic acid, often abbreviated DCA, is an acid analogue of acetic acid in which two of the three hydrogen atoms of the methyl group have been replaced by chlorine atoms.

    Products: Bichloracetic Acid 100%
  7. Drug

    Teduglutide

    go.drugbank.com/drugs/DB08900
    ApprovedInvestigational

    The significance of this substitution is that teduglutide is longer acting than endogenous GLP-2 as it is more resistant to proteolysis from dipeptidyl peptidase-4. FDA approved on December 21, 2012. … Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine).

    Products: REVESTIVE® 5 MG
  8. Drug

    Gilteritinib

    go.drugbank.com/drugs/DB12141
    ApprovedInvestigational

    [A40036] It is a pyrazinecarboxamide derivative that showed high selectivity to FLT3 preventing the c-Kit -driven myelosuppression observed in other therapies. … [A40044] Gilteritinib was developed by Astellas Pharma and FDA approved on November 28, 2018.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: XOSPATA 40 MG FİLM KAPLI TABLET, 84 ADET
  9. Drug

    Benzyl benzoate

    go.drugbank.com/drugs/DB00676
    Approved

    It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies. … Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.

    International brands: BE BOProducts: BENGAL LOSYON, 200 ML, BENZOGALE EMULSIYON 200 ML
  10. Drug

    Padimate O

    go.drugbank.com/drugs/DB11570
    Approved

    Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA [L2153]. … It is a structurally-related compound to [DB02362] that absorbs UV-B rays to prevent photodamage.

    Synonyms: Padimate O, Padimate-OMixtures: Vichy-lait Solaire SPF 10, Kiss My Face SPF 18 Lip Balm