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Interferon alfa
go.drugbank.com/drugs/DB05258ApprovedInvestigationalWithdrawnNatural interferon alpha or Multiferon is obtained from the leukocyte fraction of human blood following induction with Sendai virus. Interferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromato...
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsResveratrol
go.drugbank.com/drugs/DB02709InvestigationalResveratrol (3,5,4'-trihydroxystilbene) is a polyphenolic phytoalexin. It is a stilbenoid, a derivate of stilbene, and is produced in plants with the help of the enzyme stilbene synthase. It exists as cis-(Z) and trans-(E) isomers. The t...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersBrefeldin A
go.drugbank.com/drugs/DB07348ExperimentalA metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A Inhibitors(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE
go.drugbank.com/drugs/DB07621ExperimentalCategories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme Inhibitors9-Methylguanine
go.drugbank.com/drugs/DB02489ExperimentalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesAlbinterferon Alfa-2B
go.drugbank.com/drugs/DB05396InvestigationalAlbumin-interferon alpha (Albuferon) is a novel, long-acting form of interferon alpha. Recombinant interferon alpha is approved for the treatment of hepatitis C, hepatitis B, and a broad range of cancers. Human Genome Sciences modified i...
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsMavorixafor
go.drugbank.com/drugs/DB05501ApprovedInvestigationalMavorixafor is a CXC chemokine receptor 4 (CXCR4) antagonist.
Categories: CXC Chemokine Receptor 4 Antagonist, P-glycoprotein inhibitorsLevoketoconazole
go.drugbank.com/drugs/DB05667ApprovedCushing's syndrome (CS) is underpinned by chronic hypercortisolism leading to multisystem morbidity, including effects on the cardiovascular and endocrine systems, metabolic syndrome with accompanying changes in body composition, neurops...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesAldesleukin
go.drugbank.com/drugs/DB00041ApprovedInvestigationalAldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 ge...
Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 CYP3A InhibitorsSomatotropin
go.drugbank.com/drugs/DB00052ApprovedInvestigationalHuman growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during c...
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 Inducers