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Vismodegib
go.drugbank.com/drugs/DB08828ApprovedInvestigationalThe Hedgehog signaling pathway plays an important role in the development of organs and tissues during embryogenesis. … Afterwards, it is silenced in all cells and tissues, except for hair, skin and stem cells.
Synonyms: 2-chloro-N-(4-chloro-3-pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide, Benzamide, 2-chloro-N-(4-chloro-3-(2-pyridinyl)phenyl)-4-(methylsulfonyl)-Products: Erigib 150 mg Sert Kapsül, 28 ADET, ERIVEDGE 150 MG SERT KAPSÜL ,28 KAPSÜLDisulfiram
go.drugbank.com/drugs/DB00822ApprovedInvestigationalA carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol.
Categories: Drugs Used in Alcohol Dependence, Drugs Used in Addictive DisordersSynonyms: N,N,N',N'-tetraethylthiuram disulfide, 1,1'-dithiobis(N,N-diethylthioformamide)Prednicarbate
go.drugbank.com/drugs/DB01130ApprovedIt is used in the treatment of inflammatory skin diseases, such as atopic dermatitis. … IL-1a is also found in fibroblasts, where it is responsible for proliferation, collagenase induction and IL-6 synthesis, which are related to skin thickness.
International brands: Dermatop E EmollientProducts: PREDNICARBGALEN 2.5 MG/G, DERMATOP 2.5 MG/G KREM, 30 GPentamidine
go.drugbank.com/drugs/DB00738ApprovedInvestigationalAntiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients.
Products: PENTACARINAT ® 300 MG, DBL PENTAMIDINE ISETHIONATE FOR INJECTION BP 300 mg/vialUrokinase
go.drugbank.com/drugs/DB00013ApprovedInvestigationalWithdrawnUrokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and isoleucine 159 to yield active urokinase. … [A191943] Urokinase was granted FDA approval on 16 January 1978.[L12138]
Products: UROCHINASI EG, UROKINASE-GREEN CROSS INJ. 60,000 iu/vialReboxetine
go.drugbank.com/drugs/DB00234ApprovedInvestigationalWithdrawnReboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD.
Products: Edronax 4 mg - Tabletten, EDRONAX 4 MG TABLET, 60 ADETPyrimethamine
go.drugbank.com/drugs/DB00205ApprovedInvestigationalVet approvedOne of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
Mixtures: SULFADOXINA 500 MG + PIRIMETAMINA 25 MG TABLETASProducts: DARAPRIM 25 MG TABLETASSodium phosphate, monobasic
go.drugbank.com/drugs/DB09449ApprovedInvestigationalSodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.
Mixtures: ENEMA 161 MG/ML+59 MG/ML REKTAL ÇÖZELTİ, 210 ML, RECTUS 161 MG/ML + 59 MG/ML REKTAL ÇÖZELTİ, 210 MLProducts: BT ORAL SOLUSYON 45 ML, BT ORAL SOLUSYON 90 MLTolfenamic acid
go.drugbank.com/drugs/DB09216Approved[A31824] It was discovered by scientists at Medica Pharmaceutical Company in Finland. It is used in the UK as a treatment for migraine under the name of Clotam. … [L1292] In the US, it presents a Status class I by the FDA. By the European Medicine Agency, it was granted in 2016 with the status of orphan for the treatment of supranuclear palsy.[L1291]
Products: TOLFEDINE TABLETS 6 MG, TOLFEDINE TABLET 60 MGNeratinib
go.drugbank.com/drugs/DB11828ApprovedInvestigationalNeratinib was approved in July 2017 for use as an extended adjuvant therapy in Human Epidermal Growth Factor Receptor 2 (HER2) positive breast cancer. … Neratinib is currently under investigation for use in many other forms of cancer.
Products: NERLYNX FILM-COATED TABLETS 40 MG, NERLYNX (neratinib) Film-Coated Tablets 40 mg