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Miltefosine
go.drugbank.com/drugs/DB09031ApprovedInvestigationalIt can be administered topically or orally and is only indicated in patients aged 12 years or older. … It is currently the only recognized oral agent used to treat visceral, cutaneous, and mucosal forms of leishmaniasis, a neglected tropical disease.
Thonzonium
go.drugbank.com/drugs/DB09552ApprovedIt is widely used as an additive to in ear and nasal drops to enhance dispersion and penetration of cellular debris and exudate, thereby promoting tissue contact of the administered medication. … A common pharmaceutical formulation of thonzonium bromide is cortisporin-TC ear drops. It is also reported that thonzonium also confers an antifungal property and antiresorptive effect on bone.
Xenon Xe-129
go.drugbank.com/drugs/DB17386ApprovedInvestigationalLung MRIs are challenging due to the low proton density of this tissue, as well as the presence of artifacts due to respiration and cardiovascular pulsation movement and air–tissue interfaces. … They undergo a process that increases nuclear polarization up to five orders of magnitude, leading to a higher MRI signal.
Categories: Diagnostic Uses of ChemicalsSynonyms: Xenon, isotope of mass 129m(8.88 d), Xenon, isotope of mass 129Darolutamide
go.drugbank.com/drugs/DB12941ApprovedInvestigationalDarolutamide is a nonsteroidal androgen receptor antagonist for the treatment of castrate-resistant, non-metastatic prostate cancer (nmCRPC). … The goal of treatment with darolutamide is to delay the progression of prostate cancer to metastatic disease, increasing quality of life and life expectancy for those with advanced prostate cancer.
Obiltoxaximab
go.drugbank.com/drugs/DB05336ApprovedObiltoxaximab is a chimeric IgG1 kappa monoclonal antibody (mAb) that binds the PA component of B. anthracis toxin. It has an approximate molecular weight of 148 kDa. … Obiltoxaximab, an affinity-enhanced monoclonal antibody (Mab), is used for prevention and treatment of infection and death caused by anthrax toxin.
DL-Methylephedrine
go.drugbank.com/drugs/DB11278ApprovedMethylephedrine is a sympathomimetic amine that appears in various over-the-counter cough and cold medications throughout the world [L2838], [L2839], [L2840]. … The abuse of methylephedrine-containing medications has been reported in Japan. Methylephedrine is not legally available in the United States, but has been identified in cases of drug abuse [L2836].
Salts: DL-Methylephedrine hydrochlorideSynonyms: DL-Methylephedrine, Methylephedrine, DL-Bazedoxifene
go.drugbank.com/drugs/DB06401ApprovedInvestigationalBazedoxifene is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. … In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis.
Categories: Sex Hormones and Modulators of the Genital SystemCopper gluconate
go.drugbank.com/drugs/DB11246ApprovedInvestigationalCopper gluconate is a copper salt of D-gluconic acid that displays a light blue to bluish-green color. … According to the good manufacturing or feeding practice by the FDA, copper gluconate is used as a nutrient or dietary supplement and is generally recognized as safe for use at a level not exceeding 0.005
Mixtures: Vitamin A C E W.niacinam.beta Car.and Min., Vp-heme ObSodium zirconium cyclosilicate
go.drugbank.com/drugs/DB14048ApprovedInvestigational[L2933] Approval of the medication is supported by data from three double-blind, placebo-controlled trials and two open-label trials which showed that the onset of action was approximately 1.0 hour and … acts as a highly selective potassium removing agent.
Categories: Compounds used in a research, industrial, or household setting, Drugs for Treatment of Hyperkalemia and HyperphosphatemiaCarboprost tromethamine
go.drugbank.com/drugs/DB00429ApprovedInvestigationalA nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy.