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Histrelin
go.drugbank.com/drugs/DB06788ApprovedInvestigationalWithdrawn[L41710] GnRH agonists are the first line of treatment for children with central precocious puberty (CPP) due to their capacity to reduce LH levels and the concentration of sex steroids. … As the product Supprelin LA, histrelin is indicated for the treatment of CPP in children (approved by the FDA in May 2007).[L41700]
Synonyms: [(im-Bzl)-D-His6,Pro9-NEt]-gonadotropin releasing hormone, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-1-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamideLasofoxifene
go.drugbank.com/drugs/DB06202ApprovedInvestigationalWithdrawnIt gained approval by European Commission in March 2009. … It was initially developed as Oporia by Pfizer as a treatment for postmenopausal osteoporosis and vaginal atrophy, in which were both rejected for approval by FDA.
Aloe vera leaf
go.drugbank.com/drugs/DB13906ApprovedInvestigationalWhile aloe vera has a long history of commercial uses, it is still widely used in cosmetic, food and pharmaceutical products. … It is a perennial succulent xerophyte with elongated leaves that contain a clear gel.
Mixtures: Re-action E, Nail Care PenProducts: Shaping Patch SetChlorphentermine
go.drugbank.com/drugs/DB01556ApprovedIllicitWithdrawn(From Martindale, The Extra Pharmacopoeia, 30th ed, p1223) … A sympathomimetic agent that was formerly used as an anorectic. It has properties similar to those of dextroamphetamine. It has been implicated in lipid storage disorders and pulmonary hypertension.
Natalizumab
go.drugbank.com/drugs/DB00108ApprovedInvestigational[L48041] While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it was withdrawn from the market following multiple reports of fatal progressive multifocal leukoencephalopathy … In 2006, the FDA reintroduced the drug to the market for multiple sclerosis.[A261326] Natalizumab was further approved by the FDA for the treatment of Crohn's Disease in January 2008.
Products: TYSABRI 300 MG I.V. INFUZYON ICIN KONSANTRE COZELTI ICEREN FLAKON, 1 ADET, Tysabri 150 mg SC Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör (2 adet)Voretigene neparvovec
go.drugbank.com/drugs/DB13932ApprovedInvestigationalIt is not pathogenic and it causes a very mild immune response. … Voretigene Neparvovec-rzyl (VN-rzyl) is an adeno-associated virus vector-based gene therapy.[L1094] An adeno-associated virus is a small virus that infects humans and other primates.
Synonyms: VN-rzylRabies immune globulin, human
go.drugbank.com/drugs/DB11603ApprovedIf IMOGAM Rabies Pasteurized is not administered as recommended at the initiation of the post-exposure rabies vaccine series, it can be administered up to eight days following the first dose of the rabies … Committee on Immunization Practices (ACIP), and the World Health Organization (WHO).
Products: Imogam Rabies-HT, Rabipur Pulver und Lösungsmittel zur Herstellung einer Injektionslösung in einer FertigspritzeHuman papillomavirus type 6 L1 capsid protein antigen
go.drugbank.com/drugs/DB10299ApprovedInvestigationalIt is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) types 6, 11, 16 and 18. … Human papillomavirus type 6 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection.
Mixtures: GARDASIL® 9 VACUNA RECOMBINANTE NONAVALENTE CONTRA EL VIRUS DEL PAPILOMA HUMANO, GARDASIL® 9 VACUNA RECOMBINANTE NONAVALENTE CONTRA EL VIRUS DEL PAPILOMA HUMANOPafolacianine
go.drugbank.com/drugs/DB15413ApprovedInvestigational[L39332] It is currently under investigation for use in FRα-positive pituitary adenoma, lung cancer,[A242577] and renal-cell carcinoma, which is thought to be the second-highest folate receptor-expressing … It emits fluorescence within a range of 790 nm to 815 nm with a peak emission of 796 nm.
Categories: Compounds used in a research, industrial, or household settingTetrabenazine
go.drugbank.com/drugs/DB04844ApprovedIt is a monoamine depletor and used as symptomatic treatment of chorea associated with Huntington's disease. FDA approved on August 15, 2008. … A drug formerly used as an antipsychotic but now used primarily in the symptomatic treatment of various hyperkinetic disorders.
Products: Dystardis 25 mg Tabletten, Tetmodis 25 mg Tabletten