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Displaying results 1761 - 1770 of 10000 in total
  1. Target

    Sodium/potassium-transporting ATPase subunit beta-2

    go.drugbank.com/bio_entities/BE0005018
    TransporterTargetHumans

    This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known

    Synonyms: Adhesion molecule in glia
  2. Target

    Glycogen phosphorylase, muscle form

    go.drugbank.com/bio_entities/BE0000916
    TargetHumans

    Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular

    Polypeptides: Glycogen phosphorylase, muscle form
  3. Target

    Glycogen phosphorylase, brain form

    go.drugbank.com/bio_entities/BE0002150
    TargetHumans

    Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates (PubMed:3346228). … Phosphorylase is an important allosteric enzyme in carbohydrate metabolism (PubMed:3346228).

    Polypeptides: Glycogen phosphorylase, brain form
  4. Drug

    Balsam of Peru

    go.drugbank.com/drugs/DB11482
    ApprovedNutraceuticalVet approved

    as safe (GRAS). … [F117] Under the FDA, balsam of Peru is considered as an inactive ingredient to be used for approved drug products[L2878] as well as an approved food additive under the categorization of generally recognized

    Mixtures: Keloid Healer Synergy for treatment of keloids, Stroke II SynergyCategories: Compounds used in a research, industrial, or household setting
  5. Drug

    Mepyramine

    go.drugbank.com/drugs/DB06691
    ApprovedVet approved

    It has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered to be an unapproved prescription medication used for cough, cold, or allergic conditions. … Mepyramine, or pyrilamine, targets the H1 receptor. It is a first generation antihistamine. However, it rapidly permeates the brain and so often causes drowsiness as a side effect.

    Synonyms: N-(p-methoxybenzyl)-N',N'-dimethyl-N-(α-pyridyl)ethylenediamine, N',N'-dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)ethylenediamineMixtures: Bronchodex Fort-DM Syr, Neo AC
  6. Drug

    Asparaginase Erwinia chrysanthemi

    go.drugbank.com/drugs/DB08886
    ApprovedInvestigational

    [A236344] Studies show that substitution of _Erwinia_ asparaginase for _E. coli_-derived asparaginase following an allergic reaction has been safe and effective. … [L149] In June 2021, the recombinant form of asparaginase _Erwinia chrysanthemi_ was approved by the FDA as a component of a chemotherapy regimen to treat acute lymphoblastic leukemia and lymphoblastic

  7. Drug

    Tofacitinib

    go.drugbank.com/drugs/DB08895
    ApprovedInvestigational

    It is approved by the FDA for treatment of moderate to severe rheumatoid arthritis that responds inadequately to methotrexate or in those who are intolerant to methotrexate. … Besides rheumatoid arthritis, tofacitinib has also been studied in clinical trials for the prevention of organ transplant rejection, and is currently under investigation for the treatment of psoriasis.

    Mixtures: XELJANZ XR, XELJANZ XRCategories: Biologics for Rheumatoid Arthritis Treatment
  8. Indication

    Back Pain, Acute

    go.drugbank.com/conditions/DBCOND0055939
    Drugs: Flurbiprofen · Nonivamide · Thiocolchicoside
    Synonyms: Pain in back
  9. Indication

    Cognitive Dysfunctions

    go.drugbank.com/conditions/DBCOND0063316
    Drugs: Choline alfoscerate · Ginkgo biloba · Piracetam · Pyritinol
    Synonyms: Disturbance in cognition
  10. Drug

    Prenylamine

    go.drugbank.com/drugs/DB04825
    ApprovedWithdrawn

    Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.

    Synonyms: N-(3,3-Diphenylpropyl)-alpha-methylphenaethylamin, N-(3,3-Diphenylpropyl)-alpha-methylphenethylamineCategories: Vasodilators Used in Cardiac Diseases