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Displaying results 1771 - 1780 of 10000 in total
  1. Drug

    2-Acetyl-3-[(4-Amino-2-Methyl-5-Pyrimidinyl)Methyl]-4-Methyl-5-(4,6,6-Trihydroxy-3,5-Dioxa-4,6-Diphosphahex-1-Yl)Thiazolium Inner Salt P,P'-Dioxide

    go.drugbank.com/drugs/DB02410
    Experimental

    Synonyms: 2-Acetyl-3-[(4-Amino-2-Methyl-5-Pyrimidinyl)Methyl]-4-Methyl-5-(4,6,6-Trihydroxy-3,5-Dioxa-4,6-Diphosphahex-1-Yl)Thiazolium Inner Salt P,P'-Dioxide
  2. Target

    Glycogen phosphorylase, liver form

    go.drugbank.com/bio_entities/BE0000007
    TargetHumans

    Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular

    Polypeptides: Glycogen phosphorylase, liver form
  3. Drug

    Gabapentin

    go.drugbank.com/drugs/DB00996
    ApprovedInvestigational

    Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid ([GABA]) that was first approved for use in the United States in 1993. … [L8717] It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic pain.

    Mixtures: GAVINDO N, Lipritin IIProducts: Nu-gabapentin Capsules
  4. Drug

    Levodropropizine

    go.drugbank.com/drugs/DB12472
    Investigational

    Levodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine).

    Products: LEVOPRONT(R) JARABE, LEVOZOPIN FORT 60MG/5ML ŞURUP, 75 ML
  5. Drug

    Bupropion

    go.drugbank.com/drugs/DB01156
    ApprovedInvestigational

    [A6399,A178810] Bupropion was originally classified as an "atypical" antidepressant because it does not exert the same effects as the classical antidepressants such as Monoamine Oxidase Inhibitors ( … [F4624] When used in combination with [naltrexone] in the marketed product ContraveⓇ for chronic weight management, the two components are thought to have effects on areas of the brain involved in the

    Categories: Antidepressive Agents Indicated for DepressionProducts: BUDEP XR® TABLETAS, WELLBUTRIN XR 150 MG
  6. Drug

    CIGB-258 peptide

    go.drugbank.com/drugs/DB15809
    Experimental

    As of 2020, The Center for Genetic Engineering and Biotechnology (CIGB) in Havana, Cuba, is testing the treatment efficacy of this peptide in patients with COVID-19 who are under intensive therapy regimens … CIGB-258 is a peptide that is immunoregulatory and derived from heat shock protein 60 of the cellular variant.

  7. Target

    Sodium/potassium-transporting ATPase subunit beta-2

    go.drugbank.com/bio_entities/BE0005018
    TransporterTargetHumans

    This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known

    Synonyms: Adhesion molecule in glia
  8. Target

    Glycogen phosphorylase, muscle form

    go.drugbank.com/bio_entities/BE0000916
    TargetHumans

    Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular

    Polypeptides: Glycogen phosphorylase, muscle form
  9. Target

    Glycogen phosphorylase, brain form

    go.drugbank.com/bio_entities/BE0002150
    TargetHumans

    Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates (PubMed:3346228). … Phosphorylase is an important allosteric enzyme in carbohydrate metabolism (PubMed:3346228).

    Polypeptides: Glycogen phosphorylase, brain form
  10. Drug

    Rezafungin

    go.drugbank.com/drugs/DB16310
    ApprovedInvestigational

    [A258403] In March 2023, the FDA approved rezafungin for injection for the treatment of candidemia and invasive candidiasis in adults with limited or no alternative treatment options. … [L45633,L45658] It was subsequently approved in the EU in November of the same year. [L52745]

    Synonyms: Rezafungin ion, Echinocandin B, 1-((4R,5R)-4-hydroxy-N2-((4''-(pentyloxy)(1,1':4',1''-terphenyl)-4-yl)carbonyl)-5-(2-(trimethylammonio)ethoxy)-l-ornithine)-4-((4S)-4-hydroxy-4-(4-hydroxyphenyl)-l-allothreonine)-