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Zonisamide
go.drugbank.com/drugs/DB00909ApprovedInvestigationalZonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures. Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels, leading to a reduction of T-type calcium c...
Synonyms: Benzo[d]isoxazol-3-yl-methanesulfonamideCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesZansecimab
go.drugbank.com/drugs/DB16389InvestigationalZansecimab is under investigation in clinical trial NCT04342897 (A Study of LY3127804 in Participants With COVID-19).
Calcium glubionate anhydrous
go.drugbank.com/drugs/DB13142ApprovedCalcium glubionate (or glubionate calcium) is a mineral supplement to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets.
Synonyms: (D-gluconato)(lactobionato)calcium, Calcium D-gluconate lactobionateRevefenacin
go.drugbank.com/drugs/DB11855ApprovedInvestigationalRevefenacin is a novel biphenyl carbamate tertiary amine agent that belongs to the family of the long-acting muscarinic antagonists (LAMA). The labile primary amide in the structure produces a "soft-drug" site that allows rapid systemic ...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesChlorthalidone
go.drugbank.com/drugs/DB00310ApprovedInvestigationalChlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. Chlorthalidone improves blood pressure and swelling by preventi...
Bacampicillin
go.drugbank.com/drugs/DB01602ApprovedWithdrawnBacampicillin is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration. During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestin...
Synonyms: 1'-ethoxycarbonyloxyethyl-(6-D-α-aminophenylacetamido)penicillanateSiagoside
go.drugbank.com/drugs/DB12351InvestigationalSiagoside completed phase 2 trials for parkinson's disease (PD) treatment. Sygen appears to be beneficial in patients with severe spinal cord injury.
Bucetin
go.drugbank.com/drugs/DB13278ApprovedWithdrawnBucetin is an analgesic and antipyretic medication which was approved for use in Germany but was withdrawn from the market in 1986 due to renal toxicity caused by the medication.[A175636]