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Valbenazine
go.drugbank.com/drugs/DB11915ApprovedInvestigationalThe reduction in chorea severity was observed as early as 2 weeks after starting treatment with an initial dose of 40 mg.[L47910] … Valbenazine is a modified metabolite of [tetrabenazine], and it is currently being approved for the treatment of various movement disorders, particularly tardive dyskinesia and chorea associated with Huntington's
Categories: Heterocyclic Compounds, 2-Ring, Vesicular Monoamine Transporter 2 InhibitorProducts: REMLEAS HARD CAPSULES 40 MGDobesilic acid
go.drugbank.com/drugs/DB13529InvestigationalProducts: X-VEN 500 MG KAPSÜL,30 ADET, X-VEN 500 MG KAPSÜL,60 ADETDronedarone
go.drugbank.com/drugs/DB04855ApprovedInvestigationalIt is managed by rate control, rhythm control, prevention of thromboembolic events, and treatment of the underlying disease. … [T28] Commonly marketed as Multaq®, dronedarone was approved by the FDA in July 2009 and Health Canada in August 2009.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesSynonyms: N-(2-butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)-methanesulfonamide, N-(2-butyl-3-(p-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)methanesulfonamideTinzaparin
go.drugbank.com/drugs/DB06822ApprovedInvestigationalIt is an anticoagulant and considered an antithrombotic. Tinzaparin must be given either subcutaneously or parenterally. … It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons.
Products: INNOHEP INYECTABLE VIAL 2 MG 10.000 UI/ML., INNOHEP INJECTION 14, 000 Anti-Xa IU/0.7mlCoal tar
go.drugbank.com/drugs/DB11082ApprovedIt has been indicated for local relief of itching, dryness, and irritation caused by psoriasis, seborrhea and eczema.
Mixtures: PREPARED COAL TAR 5% ET SALICYLIC ACID 2% OINTMENT, Multi-action Denorex 2-IN-1 Dandruff Shampoo + ConditionerProducts: COAL TAR SOLUTION 10% IN AQUEOUS CREAM, Jamp-coal Tar 10%SO-101
go.drugbank.com/drugs/DB05345ExperimentalDoxepin has been prescribed for more than 40 years for the treatment of depression and anxiety at dosages typically ranging from 75 mg to 300 mg per day. … SO-101(Silenor) is a low-dose oral tablet formulation of doxepin hydrochloride that is patent protected for its use in insomnia.
Brivudine
go.drugbank.com/drugs/DB03312ApprovedInvestigationalBrivudine is used in the treatment of herpes zoster. Although not approved in the U.S. or Canada, it is approved in several European countries.
Synonyms: (E)-5-(2-Bromovinyl)-deoxyuridineProducts: Mevir 125 mg Tabletten, ZOSTEX 125 MG TABLET, 7 ADETTropisetron
go.drugbank.com/drugs/DB11699ApprovedInvestigationalWithdrawnAs a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting … Tropisetron is an indole derivative with antiemetic activity.
Categories: Heterocyclic Compounds, 2-Ring, Serotonin 5-HT3 Receptor AntagonistsProducts: NAVOBAN 5 MG 1 AMPUL, Navoban 5 mg - AmpullenUrokinase
go.drugbank.com/drugs/DB00013ApprovedInvestigationalWithdrawn[A191943] Urokinase remains connected between these 2 chains by a sulfhydryl bond.[A191943] Urokinase was granted FDA approval on 16 January 1978.[L12138] … Urokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and isoleucine 159 to yield active urokinase.
Products: UROCHINASI EGIxabepilone
go.drugbank.com/drugs/DB04845ApprovedInvestigationalIt was FDA approved on October 16, 2007, for the treatment of unresponsive aggressive metastatic or locally advanced breast cancer. … Ixabepilone is an epothilone B analog developed by Bristol-Myers Squibb as a cancer drug.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: IXEMPRA (FOR INJECTION 15 MG), IXEMPRA FOR INJECTION 15 MG