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Prednisolone Action Action Pathway New
smpdb.ca/view/SMP0122639Drug actionPrednisolone is a corticosteroid drug that is used for inflammation, GI diseases, allergies and immunosuppression along with other uses. As prednisolone is a glucocorticoid, it's mechanism of actions is that of the glucocorticoid respons...
Enzymes: Prostaglandin E synthaseBetamethasone Action Pathway
smpdb.ca/view/SMP0126176Drug actionBetamethasone is administered in many different routes; eye drops, oral tablets, rectal enema, topical cream, and many others. … Betamethasone is a long-acting and systemic corticosteroid used to relieve inflammation in various conditions, including allergic states, dermatologic disorders, gastrointestinal diseases, and hematological
Enzymes: Prostaglandin E synthaseClobetasone Action Pathway
smpdb.ca/view/SMP0126192Drug actionIn ophthalmology, clobetasone butyrate eye drops have been shown to be safe and effective in the treatment of dry eyes in Sjögren's Syndrome. … In dermatology, topical clobestasone helps to reduce the itchiness and erythema associated with eczema and dermatitis.
Drugs: Glutathione · Dinoprostone · Calcium · Prostaglandin D2 · Mesoheme · Prostaglandin G2 +2 moreEnzymes: Prostaglandin E synthaseHydrocortamate Action Pathway
smpdb.ca/view/SMP0126237Drug actionHydrocortamate is a synthetic steroid hormone used for its anti-inflammatory or immunosuppressive properties to treat corticosteroid-responsive dermatoses. Hydrocortamate binds to the cytosolic glucocorticoid receptor. By binding to the ...
Enzymes: Prostaglandin E synthasePrednicarbate Action Pathway
smpdb.ca/view/SMP0126238Drug actionPrednicarbate is a relatively new topical corticosteroid. It displays similar potency as hydrocortisone and has a favorable benefit-risk ratio, with an inflammatory action similar to that of a medium potency corticosteroid, but with a lo...
Enzymes: Prostaglandin E synthaseFluticasone Action Pathway
smpdb.ca/view/SMP0126244Drug actionFluticasone is a corticosteroid used in the treatment of corticosteroid-responsive dermatoses, asthma, and moderate to severe Chronic Obstructive Pulmonary Disease (COPD).
Drugs: Glutathione · Dinoprostone · Calcium · Prostaglandin D2 · Mesoheme · Prostaglandin G2 +2 moreEnzymes: Prostaglandin E synthaseStrontium ranelate
go.drugbank.com/drugs/DB09267ApprovedWithdrawnAvailable for prescription use for a time in some parts of the world as Protelos (strontium ranelate) 2 g granules for oral suspension by Servier, it was ultimately discontinued in 2016-2017 owing to an … It is therefore promoted as a "dual action bone agent" (DABA) indicated for use in treatment of severe osteoporosis.
Mixtures: FULLBONE D3 2 G/800 IU EFERVESAN TABLET, 30 ADET, FULLBONE D3 2 G/800 IU EFERVESAN TABLET, 60 ADETCategories: Heterocyclic Compounds, 1-RingGabapentin
go.drugbank.com/drugs/DB00996ApprovedInvestigationalGabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid ([GABA]) that was first approved for use in the United States in 1993. … making it unlikely to participate in pharmacokinetic drug interactions.
Synonyms: 1-(Aminomethyl)cyclohexaneacetic acidMixtures: GAVINDO N, Lipritin IIDibotermin alfa
go.drugbank.com/drugs/DB11639ApprovedInvestigationalDibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant Chinese Hamster Ovary (CHO) cell line [FDA Label]. … BMP-2 is a potent osteoinductive protein that plays a critical role in the differentiation of osteoprogenitor cells into osteoblasts, thus promoting bone and cartilage formation [A31952].
Synonyms: BMP 2, BMP-2Neomycin
go.drugbank.com/drugs/DB00994ApprovedInvestigationalVet approved[L11979] It is also used in combination with [polymyxin B] sulfates and [hydrocortisone] in otic suspensions for use in the treatment of bacterial infections in the external auditory canal, including infections … [L10532] Neomycin is also used in combination with [polymyxin B] sulfates and [dexamethasone] in ophthalmic preparations for use in the treatment of inflammatory conditions and infections in the eye.
Mixtures: Water-Jel 3-in-1 Antibiotic, Zee 3-in-One First Aid AntibioticCategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index