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Maftivimab
go.drugbank.com/drugs/DB15899ApprovedInvestigationalEbola virus (EBOV) remains an important human pathogen within the _Ebolavirus_ genus, having been responsible for at least 17 known outbreaks with an average case fatality rate of 43.92%. … [A221825] Immune therapy using monoclonal antibodies (mAbs) is becoming an increasingly attractive therapeutic method to combat infectious diseases due to its rapid development, low toxicity, and high
Meperidine
go.drugbank.com/drugs/DB00454ApprovedInvestigationalA narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. … Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: ALDOLAN 100 MG/2 ML AMPUL, 5 ADET, PETHOLAN 100 MG/2 ML ENJEKSIYONLUK ÇÖZELTI, 5 ADETFlunitrazepam
go.drugbank.com/drugs/DB01544ApprovedIllicitFlunitrazepam is a benzodiazepine with pharmacologic actions similar to those of diazepam that can cause anterograde amnesia. … Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: ROHYPNOL 1, Rohypnol 1 mg - FilmtablettenTetraferric tricitrate decahydrate
go.drugbank.com/drugs/DB14520ApprovedInvestigationalTetraferric tricitrate decahydrate is an iron containing phosphate binder used to treat hyperphosphatemia and iron deficiency anemia in adults with chronic kidney disease. … [A25965] Tetraferric tricitrate decahydrate was granted FDA approval on 5 September 2014.[L9926]
Products: FERRISITA 107,7 MG/5 ML SURUP, 150 MLEvolocumab
go.drugbank.com/drugs/DB09303ApprovedInvestigationalIt is approved for both homozygous and heterozygous familial cholesterolemia as an adjunct to other first-line therapies. … Evolocumab is a human IgG2 monoclonal antibody that targets the proprotein convertase subtilisin/kexin type 9 (PCSK9).
Products: REPATHA® 140 MG/ML, REPATHA 140 MG/ML SC ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR ENJEKTOR, 1 ADETRacepinephrine
go.drugbank.com/drugs/DB11124ApprovedIt is an active ingredient in oral inhalation over-the-counter products as racepinephrine hydrochloride. … Racepinephrine is a racemic mixture consisting of d-[DB00668] and l-[DB00668] enantiomers. Epinephrine is a non-selective α- and β-adrenergic receptor agonist.
Mixtures: Gingicord W/epineph and Alum Size 2, Gingicord W Epineph and Alum Size No 1Categories: Adrenergic alpha-1 Receptor Agonists, Adrenergic alpha-2 Receptor AgonistsIndigotindisulfonic acid
go.drugbank.com/drugs/DB11577ApprovedInvestigationalThis compound is an acid-base indicator and is used in the production of food colorants and pH tests. … Indigotindisulfonic acid is a blue-colored dye with a variety of uses.
Synonyms: 2-(1,3-Dihydro-3-oxo-5-sulpho-2H-indol-2-ylidene)-3-oxoindoline-5-sulphonic acid, FD&C Blue #2Categories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household settingPizotifen
go.drugbank.com/drugs/DB06153Approved[A32532] It is a potent serotonin and tryptamine antagonist that has been used for migraine prevention for many years. … Pizotifen hydrochloride is an active ingredient in Sandomigran, which is used for the prophylactic management of migraines.
Categories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-1 Receptor AntagonistsEthyl chloride
go.drugbank.com/drugs/DB13259ApprovedWithdrawnEthyl chloride, or chloroethane, has a chemical formula C2H5Cl. It was commonly used in the production of tetraethyllead (TEL), which is an additive for gasoline. … Ethyl chloride is used as a diagnostic tool to detect a dead tooth with nonviable pulp.
Mixtures: Flouro Ethyl AerCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesMavelertinib
go.drugbank.com/drugs/DB16228InvestigationalMavelertinib is under investigation in clinical trial NCT02349633 (Study for Patients With NSCLC EGFR Mutations (Del 19 or L858R +/- T790M)).