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Erythromycin
go.drugbank.com/drugs/DB00199ApprovedInvestigationalVet approvedErythromycin is a bacteriostatic antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics which consists
Mixtures: T-stat Lot, T-stat Pad-lotProducts: T-Stat, ERITROVIER-TSoybean oil
go.drugbank.com/drugs/DB09422ApprovedInvestigationalSoybean oil-based lipid emulsion is the only FDA-approved lipid formulation for clinical use. … The major component fatty acids are linoleic (48% - 58%), oleic (17% - 30%), palmitic (9% -13%), linolenic (4% - 11%), and stearic (2.5% - 5.0%).
Mixtures: Olimel 7.6% E, Olimel 4.4% EPorfimer sodium
go.drugbank.com/drugs/DB00707ApprovedInvestigationalIt is the first drug to be approved in the use of photodynamic therapy in the United States. … The purified component of hematoporphyrin derivative, it consists of a mixture of oligomeric porphyrins.
Pirbuterol
go.drugbank.com/drugs/DB01291ApprovedWithdrawnenzyme which catalyzes the conversion of adenosine triphosphate (AlP) to cyclic-3† ,5†-adenosine monophosphate (c-AMP). … The pharmacologic effects of beta adrenergic agonist drugs, including pirbuterol, are at least in proof attributable to stimulation through beta adrenergic receptors of intracellular adenyl cyclase, the
Categories: Agents to Treat Airway Disease, Adrenergic beta-2 Receptor AgonistsSulfasalazine
go.drugbank.com/drugs/DB00795ApprovedInvestigational[A255582] Sulfasalazine fell out of favor as the drug of choice for RA due to poorly designed clinical trials in 1950 but regained interest from the clinical community in the late 1970. … [A255582] Compared to the first line treatment of RA like methotrexate, sulfasalazine is almost as efficacious as methotrexate although with slightly less tolerability.
Products: SARIDINE - EPegloticase
go.drugbank.com/drugs/DB09208ApprovedInvestigationalIn gout patients treated with pegloticase, the conversion of uric acid to allantoin leads to lower plasma uric acid concentrations. … [L42425] Pegloticase was approved by the FDA in 2014, and in 2022, the drug label included the co-administration of pegloticase and methotrexate.[L42425]
Hetacillin
go.drugbank.com/drugs/DB00739ApprovedVet approvedWithdrawnThe name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. … The bactericidal activity of Hetacillin results from the inhibition of cell wall synthesis and is mediated through Hetacillin binding to penicillin binding proteins (PBPs).
Atrasentan
go.drugbank.com/drugs/DB06199ApprovedInvestigational[L52855] In April 2025, atrasentan was granted accelerated approval by the FDA for the reduction of proteinuria in patients with primary IgA nephropathy, becoming the first endothelin A receptor antagonist … to be approved for this condition.
Categories: Endothelin Receptor Antagonists, Endothelin A Receptor AntagonistsVortioxetine
go.drugbank.com/drugs/DB09068ApprovedInvestigationalreceptor, an agonist of 5-HT1A, and an antagonist of the 5-HT3, 5-HT1D, and 5-HT7 receptors. … More specifically, vortioxetine acts via the following biological mechanisms: as a serotonin reuptake inhibitor (SRI) through inhibition of the serotonin transporter, as a partial agonist of the 5-HT1B
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin Receptor AgonistsLovastatin
go.drugbank.com/drugs/DB00227ApprovedInvestigational[A174550] Originally named Mevinolin, lovastatin belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid levels by inhibiting the … [A174580,A181409,A181535,A181538,A1793] Potency is thought to correlate to tissue permeability as the more lipophilic statins such as lovastatin are thought to enter endothelial cells by passive diffusion