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Displaying results 1781 - 1790 of 10000 in total
  1. Drug

    Dronedarone

    go.drugbank.com/drugs/DB04855
    ApprovedInvestigational

    It is managed by rate control, rhythm control, prevention of thromboembolic events, and treatment of the underlying disease. … [T28] Commonly marketed as Multaq®, dronedarone was approved by the FDA in July 2009 and Health Canada in August 2009.

    Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesSynonyms: N-(2-butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)-methanesulfonamide, N-(2-butyl-3-(p-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)methanesulfonamide
  2. Drug

    Octisalate

    go.drugbank.com/drugs/DB11062
    Approved

    It covers wavelength in the range 295-315 nm, peak at 307-310 nm. It is an ester of salicylic acid and 2-ethylhexanol. … Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen.

    Mixtures: Anew Rejuvenate 24 Hour Eye Moisturizer Hydratant Yeux 24 Heures SPF 25 Day, Ultra Defense Spray Sunscreen Écran Solaire En Vaporisateur SPF Fps 100Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Rilmenidine

    go.drugbank.com/drugs/DB11738
    ApprovedWithdrawn

    Rilmenidine has been used in trials studying the treatment of Hypertension and Chronic Kidney Disease.

    Categories: Adrenergic alpha-2 Receptor AgonistsProducts: HYPERIUM 1 MG TABLET, 30 ADET, Iterium 1 mg - Tabletten
  4. Drug

    Valbenazine

    go.drugbank.com/drugs/DB11915
    ApprovedInvestigational

    The reduction in chorea severity was observed as early as 2 weeks after starting treatment with an initial dose of 40 mg.[L47910] … Valbenazine is a modified metabolite of [tetrabenazine], and it is currently being approved for the treatment of various movement disorders, particularly tardive dyskinesia and chorea associated with Huntington's

    Categories: Heterocyclic Compounds, 2-Ring, Vesicular Monoamine Transporter 2 InhibitorProducts: REMLEAS HARD CAPSULES 40 MG
  5. Drug

    Lanatoside C

    go.drugbank.com/drugs/DB13467
    Investigational

    Products: CETO-SANOL DAMLA, 10 ML, CETO-SANOL DAMLA, 50 ML
  6. Drug

    Tinzaparin

    go.drugbank.com/drugs/DB06822
    ApprovedInvestigational

    It is an anticoagulant and considered an antithrombotic. Tinzaparin must be given either subcutaneously or parenterally. … It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons.

    Products: INNOHEP INYECTABLE VIAL 2 MG 10.000 UI/ML., INNOHEP INJECTION 14, 000 Anti-Xa IU/0.7ml
  7. Drug

    Polyvinyl alcohol

    go.drugbank.com/drugs/DB11060
    Approved

    It has varying roles in commercial and industrial applications such as papermaking, textiles, and printing. … Polyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes [L2826].

    Mixtures: SICCAPROTECT 10 ML GOZ DAMLASI, Premier Value Eye Drops MtCategories: Compounds used in a research, industrial, or household setting
  8. Drug

    Encorafenib

    go.drugbank.com/drugs/DB11718
    ApprovedInvestigational

    [L3344] On June 27, 2018, the Food and Drug Administration approved encorafenib and [binimetinib] (BRAFTOVI and MEKTOVI, Array BioPharma Inc.) in combination for patients with unresectable or metastatic … Mutations in this gene, most frequently the V600E mutation, are the most commonly identified cancer-causing mutations in melanoma, and have been isolated in various other cancers as well, including non-Hodgkin

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersProducts: BRAFTOVİ 75 MG SERT KAPSÜL, 42 ADET, BRAFTOVI® 75 MG CÁPSULAS
  9. Drug

    Regorafenib

    go.drugbank.com/drugs/DB08896
    ApprovedInvestigational

    It is used for the treatment of metastatic colorectal cancer, advanced gastrointestinal stromal tumours, and hepatocellular carcinoma. FDA approved on September 27, 2012. … Regorafenib is an orally-administered inhibitor of multiple kinases.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InhibitorsProducts: STIVARGA 40 MG FILM KAPLI TABLET ,84 ADET, STIVARGA 40 MG TABLETA RECUBIERTA
  10. Drug

    Primidone

    go.drugbank.com/drugs/DB00794
    ApprovedVet approved

    [L11112] Primidone was developed by J Yule Bogue and H C Carrington in 1949.[A189522] Primidone was granted FDA Approval on 8 March 1954.[L11112] … Primidone is an anticonvulsant used to treat essential tremor as well as grand mal, psychomotor, and focal epileptic seizures.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersSynonyms: 2-deoxyphenobarbital, 5-Phenyl-5-ethyl-Hexahydropyrimidine-4,6-dione