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Displaying results 171 - 180 of 367 in total
  1. Target

    Calpain-3

    go.drugbank.com/bio_entities/BE0003470
    TargetHumans

    Calcium-regulated non-lysosomal thiol-protease. Proteolytically cleaves CTBP1 at 'His-409'. Mediates, with UTP25, the proteasome-independent degradation of p53/TP53 (PubMed:23357851, PubMed:27657329)

    Synonyms: Calcium-activated neutral proteinase 3, Muscle-specific calcium-activated neutral protease 3Function: calcium ion binding
  2. Target

    Protein S100-B

    go.drugbank.com/bio_entities/BE0001177
    TargetHumans

    Small zinc- and- and calcium-binding protein that is highly expressed in astrocytes and constitutes one of the most abundant soluble proteins in brain (PubMed:20950652, PubMed:6487634). … May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity (PubMed:22399290)

    Synonyms: S100 calcium-binding protein BFunction: calcium ion binding
  3. Target

    Protein S100-P

    go.drugbank.com/bio_entities/BE0001191
    TargetHumans

    May function as calcium sensor and contribute to cellular calcium signaling. … In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial

    Synonyms: S100 calcium-binding protein P
  4. Target

    Acetyl-coenzyme A synthetase, cytoplasmic

    go.drugbank.com/bio_entities/BE0000350
    TargetEnzymeHumans

    Acetate is the preferred substrate (PubMed:10843999, PubMed:28003429, PubMed:38369012, PubMed:39561764). Can also utilize propionate with a much lower affinity (PubMed:38369012). … Nuclear ACSS2 promotes glucose deprivation-induced lysosomal biogenesis and autophagy, tumor cell survival and brain tumorigenesis (PubMed:28552616).

    Synonyms: Acetate--CoA ligase
  5. Target

    Sulfide-quinone reductase

    go.drugbank.com/bio_entities/BE0004025
    TargetEnzymeAquifex aeolicus (strain VF5)

    Catalyzes the oxidation of hydrogen sulfide, with the help of a quinone.

    Polypeptides: Sulfide-quinone reductase
  6. Target

    Sulfide-quinone reductase

    go.drugbank.com/bio_entities/BE0004026
    TargetAcidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / NCIB 8455)

    Catalyzes the oxidation of hydrogen sulfide, with the help of a quinone.

    Polypeptides: Sulfide-quinone reductase
  7. Target

    Adiponectin receptor

    go.drugbank.com/bio_entities/BE0010287
    TargetHumans

    Required for normal glucose and fat homeostasis and for maintaining a normal body weight. … Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:12802337, PubMed:25855295). Required for normal body fat and glucose homeostasis.

    Synonyms: Progestin and adipoQ receptor family member 1, Progestin and adipoQ receptor family member I
  8. Target

    Protein S100-A16

    go.drugbank.com/bio_entities/BE0008707
    TargetHumans

    Calcium-binding protein. Binds one calcium ion per monomer (PubMed:17030513). Can promote differentiation of adipocytes (in vitro) (By similarity). … Overexpression in preadipocytes increases their proliferation, enhances adipogenesis and reduces insulin-stimulated glucose uptake (By similarity)

    Synonyms: S100 calcium-binding protein A16Function: calcium ion binding
  9. Target

    Cadmium

    go.drugbank.com/bio_entities/BE0004802
    TargetHumans

  10. Target

    Surface protein A

    go.drugbank.com/bio_entities/BE0002809
    TargetNeisseria meningitidis

    Polypeptides: Surface protein A