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Displaying results 171 - 180 of 48101 in total
  1. Drug

    Aminometradine

    go.drugbank.com/drugs/DB19365
    Approved

    Synonyms: 1-allyl-6-amino-3-ethyluracil
  2. Drug

    Dexrazoxane

    go.drugbank.com/drugs/DB00380
    ApprovedInvestigationalWithdrawn

    It appears to inhibit formation of a toxic iron-anthracycline complex. … [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy.

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingSynonyms: 2, 6-Piperazinedione, 4,4'-propylenedi-, (P)- (8CI), 2,6-Piperazinedione, 4, 4'-(1-methyl-1,2-ethanediyl)bis-, (S)- (9CI)
  3. Drug

    Clindamycin

    go.drugbank.com/drugs/DB01190
    ApprovedInvestigationalVet approved

    Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris. … The name lincomycin is derived from Lincoln, Nebraska, where it was first isolated from _Streptomyces lincolnensis_ found in a soil sample.[A190621]

    Synonyms: Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside, 7(S)-Chloro-7-deoxylincomycinInternational brands: Dalacin C, Dalacin T Topical Solution
  4. Drug

    Cabergoline

    go.drugbank.com/drugs/DB00248
    ApprovedInvestigational

    Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome.

    Synonyms: 1-ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'β-carbonyl)urea, (8R)-6-allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamideCategories: Heterocyclic Compounds with 4 or More Rings, P-glycoprotein substrates with a Narrow Therapeutic Index
  5. Drug

    Hetacillin

    go.drugbank.com/drugs/DB00739
    ApprovedVet approvedWithdrawn

    Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. … Hetacillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: (2S,5R,6R)-6-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6β-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]penicillanic acid
  6. Drug

    Levobupivacaine

    go.drugbank.com/drugs/DB01002
    ApprovedInvestigationalWithdrawn

    In particular, the specific levobupivacaine enantiomer is a worthwhile pursuit because it demonstrates less vasodilation and possesses a greater length of action in comparison to bupivacaine. … Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: (S)-1-butyl-2',6'-pipecoloxylidide, L-(-)-1-Butyl-2',6'-pipecoloxylidide
  7. Drug

    Amiloride

    go.drugbank.com/drugs/DB00594
    ApprovedInvestigational

    A pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. … This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct.

    Mixtures: Riva-amilzide 5/50 mg, Nu-amilzide 5/50 Mg TabCategories: Decreased Renal K+ Excretion, Heterocyclic Compounds, 1-Ring
  8. Drug

    2-(4-hydroxyphenyl)benzo[b]thiophen-6-ol

    go.drugbank.com/drugs/DB08773
    Experimental

    Synonyms: 2-(4-hydroxyphenyl)benzo(b)thiophene-6-ol, 2-(4-hydroxyphenyl)benzo[b]thiophen-6-ol
  9. Drug

    4-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)--BENZAMIDE

    go.drugbank.com/drugs/DB08241
    Experimental

    Synonyms: 4-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)--BENZAMIDE
  10. Drug

    Brimonidine

    go.drugbank.com/drugs/DB00484
    ApprovedInvestigational

    [A178951] It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. … Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996.

    Mixtures: Brimonidine Tartrate 0.25% / Ivermectin 1% / Metronidazole 1% / Niacinamide 4%, Combigan 2 mg/ml + 5 mg/ml AugentropfenCategories: Heterocyclic Compounds, 2-Ring, Adrenergic alpha-2 Receptor Agonists