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Alunacedase alfa
go.drugbank.com/drugs/DB15736InvestigationalAlunacedase alfa is a recombinant and soluble glycosylated form of human ACE2. This recombinant version of the enzyme has antihypertensive and potential antineoplastic activities.
Synonyms: Alunacedase alfaBintrafusp alfa
go.drugbank.com/drugs/DB15387InvestigationalBintrafusp alfa is under investigation in clinical trial NCT03833661 (M7824 Monotherapy in Locally Advanced or Metastatic Second Line (2L) Biliary Tract Cancer (Cholangiocarcinoma and Gallbladder Cancer
Synonyms: Bintrafusp alfaTroplasminogen alfa
go.drugbank.com/drugs/DB18985InvestigationalTroplasminogen alfa is under investigation in clinical trial NCT00144014 (Safety and Efficacy Study in Acute Ischaemic Stroke).
Synonyms: Troplasminogen alfaEnglumafusp alfa
go.drugbank.com/drugs/DB19341InvestigationalEnglumafusp alfa is under investigation in clinical trial NCT04077723 (A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab
Synonyms: Ensomafusp alfa, Englumafusp alfaModakafusp alfa
go.drugbank.com/drugs/DB16399InvestigationalModakafusp alfa is under investigation in clinical trial NCT03215030 (A Study to Investigate the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of TAK-573 in Participants With Refractory
Synonyms: Modakafusp alfaZamubafusp alfa
go.drugbank.com/drugs/DB32269InvestigationalZamubafusp alfa is an immunoglobulin-peptide fusion protein.[L55038] It consists of a humanized IgG1 and p5R which is a pan-amyloid reactive peptide.[L55038]
Synonyms: Zamubafusp alfaDalcinonacog alfa
go.drugbank.com/drugs/DB17707InvestigationalDalcinonacog alfa is a recombinant human factor IX (FIX) variant. It is being investigated for the treatment of hemophilia B.[A259058]
Eftilagimod alfa
go.drugbank.com/drugs/DB16150InvestigationalEftilagimod alfa is under investigation in clinical trial NCT02614833 (IMP321 (Eftilagimod Alpha) as Adjunctive to a Standard Chemotherapy Paclitaxel Metastatic Breast Carcinoma).
Synonyms: Eftilagimod alfaNanrilkefusp alfa
go.drugbank.com/drugs/DB17480InvestigationalNanrilkefusp alfa is a human fusion protein consisting of the cytokine interleukin (IL)-15 and the high-affinity binding sushi+ domain of IL-15 receptor alpha (IL-15Ra).
Synonyms: Nanrilkefusp alfaTralesinidase alfa
go.drugbank.com/drugs/DB17657InvestigationalTralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2.
Synonyms: Tralesinidase alfa