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Displaying results 171 - 180 of 691 in total
  1. Drug

    Bucelipase alfa

    go.drugbank.com/drugs/DB16664
    Investigational

    Bucelipase alfa is under investigation in clinical trial NCT00743483 (Efficacy of Bucelipase Alfa (BSSL) in Patients With Cystic Fibrosis and Pancreatic Insufficiency).

  2. Pathway

    Mitochondrial Complex II Deficiency

    smpdb.ca/view/SMP0125754
    Disease

    Interestingly, complex II deficiency gene mutation carriers may be at an increased risk for certain cancers. … Because complex II is found in the mitochondria, CII deficiency is technically considered a mitochondrial disease.

    Drugs: Pyruvic acid · Biotin · Succinic acid · NADH · ATP · Magnesium cation +4 more
    Enzymes: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
  3. Drug

    Troplasminogen alfa

    go.drugbank.com/drugs/DB18985
    Investigational

    Troplasminogen alfa is under investigation in clinical trial NCT00144014 (Safety and Efficacy Study in Acute Ischaemic Stroke).

    Synonyms: Troplasminogen alfa
  4. Drug

    Zamubafusp alfa

    go.drugbank.com/drugs/DB32269
    Investigational

    Zamubafusp alfa is an immunoglobulin-peptide fusion protein.[L55038] It consists of a humanized IgG1 and p5R which is a pan-amyloid reactive peptide.[L55038]

    Synonyms: Zamubafusp alfa
  5. Drug

    Nanrilkefusp alfa

    go.drugbank.com/drugs/DB17480
    Investigational

    Nanrilkefusp alfa is a human fusion protein consisting of the cytokine interleukin (IL)-15 and the high-affinity binding sushi+ domain of IL-15 receptor alpha (IL-15Ra).

    Synonyms: Nanrilkefusp alfa
  6. Drug

    Atexakin alfa

    go.drugbank.com/drugs/DB19234
    Investigational

    Atexakin alfa is under investigation in clinical trial NCT05435742 (SON-080 in Patients With Persistent Chemotherapy-induced Peripheral Neuropathy (CIPN)).

  7. Drug

    Englumafusp alfa

    go.drugbank.com/drugs/DB19341
    Investigational

    Englumafusp alfa is under investigation in clinical trial NCT04077723 (A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab

    Synonyms: Ensomafusp alfa, Englumafusp alfa
  8. Drug

    Lepunafusp alfa

    go.drugbank.com/drugs/DB19011
    Investigational

    Lepunafusp alfa is under investigation in clinical trial NCT04453085 (An Extension Study of JR-171-101 Study in Patients With MPS I).

    Synonyms: Lepunafusp alfa
  9. Drug

    Alunacedase alfa

    go.drugbank.com/drugs/DB15736
    Investigational

    Alunacedase alfa is a recombinant and soluble glycosylated form of human ACE2. This recombinant version of the enzyme has antihypertensive and potential antineoplastic activities.

    Synonyms: Alunacedase alfa
  10. Drug

    Lusacomfar Alfa

    go.drugbank.com/drugs/DB18526
    Experimental

    Lusacomfar Alfa is a recombinant complement factor H

    Synonyms: Lusacomfar Alfa