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Clonazepam
go.drugbank.com/drugs/DB01068ApprovedIllicitInvestigationalA benzodiazepine used to treat various seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. … Now available as a generic medication, the agent continues to see exceptionally high use as millions of prescriptions are written for the medication internationally every year.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 InhibitorsSynonyms: 5-(2-chlorophenyl)-7-nitro-1H-benzo[e][1,4]diazepin-2(3H)-one, 5-(2-chloro-phenyl)-7-nitro-1,3-dihydro-benzo[e][1,4]diazepin-2-oneSulfamethoxazole
go.drugbank.com/drugs/DB01015ApprovedInvestigational[L11830] It is generally given in combination with [trimethoprim], which inhibits a sequential step in bacterial folic acid synthesis - these agents work synergistically to block two consecutive steps … Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria.
Synonyms: 3-Sulfanilamido-5-methylisoxazole, 3-(p-Aminophenylsulfonamido)-5-methylisoxazoleMixtures: SEPTRIN IV 5 ML 10 AMPUL, METOPRIM 200 MG + 40 MG/5 ML SUSPANSIYON, 100 MLEleuthero
go.drugbank.com/drugs/DB14303ApprovedInvestigationalEleuthero is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Et Maxim.) Maxim. Root, Acanthopanacis Senticosi Radix Et Rhizoma Seu CaulisBiperiden
go.drugbank.com/drugs/DB00810ApprovedInvestigationalWithdrawnA muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. … It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2D6 InhibitorsSynonyms: 1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-yl-propan-1-ol, alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanolUracil mustard
go.drugbank.com/drugs/DB00791ApprovedIt is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage.
Synonyms: 5-[bis(2-chloroethyl)amino]-2,4(1H,3H)-pyrimidinedione, 5-(di-2-chloroethyl)aminouracilCategories: Heterocyclic Compounds, 1-RingDaunorubicin
go.drugbank.com/drugs/DB00694ApprovedInvestigationalA very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms.
Synonyms: (8S-cis)-8-acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione, Leukaemomycin CCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexErgotamine
go.drugbank.com/drugs/DB00696ApprovedA vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.
Synonyms: (5'α)-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotoman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'α-(phenylmethyl)ergotaman-3',6',18-trioneMixtures: CAFERGOT 1 MG/100 MG TABLET, 30 ADET, ERGOTAMINA 1 MG + CAFEINA 100 MG TABLETASLevomenthol
go.drugbank.com/drugs/DB00825ApprovedInvestigationalForming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration … Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils.
Mixtures: KAMFOLIN 150 MG/G+100 MG/G MERHEM, 50 G, SADRÜD % 10 + % 15 JEL, 50 GCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTrifluridine
go.drugbank.com/drugs/DB00432ApprovedInvestigationalIt displays effective antiviral activity against Herpes simplex virus type 1 and 2 [A35271]. … Trifluridine is a fluorinated pyrimidine nucleoside that is structurally related to [idoxuridine] [A35271].
Synonyms: F₃T, 5-Trifluoromethyl-2-deoxyuridineMixtures: LONSURF FILM-COATED TABLET 15 MG/6.14 MG, LONSURF FILM-COATED TABLET 15 MG/6.14 MGTribromsalan
go.drugbank.com/drugs/DB20138ApprovedWithdrawnTribromsalan is a small molecule drug. Tribromsalan has a monoisotopic molecular weight of 446.81 Da.
Synonyms: 3,4',5-tribromosalicylanilide