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Displaying results 1791 - 1800 of 10000 in total
  1. Target

    Sodium- and chloride-dependent GABA transporter 3

    go.drugbank.com/bio_entities/BE0004733
    TargetHumans

    Can also mediate transport of beta-alanine and to a lower extent that of taurine and hypotaurine (By similarity) … Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed:7874447).

    Polypeptides: Sodium- and chloride-dependent GABA transporter 3
  2. Target

    Disintegrin and metalloproteinase domain-containing protein 33

    go.drugbank.com/bio_entities/BE0019245
    TargetHumans

    Promotes and maintains a proliferative phenotype in vascular smooth muscle cells through regulation of the PI3K/AKT and ERK signaling pathways (PubMed:33982767). … Metalloprotease that cleaves and sheds the ectodomains of cell-surface proteins and thereby contributes to angiogenesis, cell differentiation, inflammation, and cell proliferation (PubMed:14676211, PubMed

    Polypeptides: Disintegrin and metalloproteinase domain-containing protein 33
  3. Drug

    Selenious acid

    go.drugbank.com/drugs/DB11127
    Approved

    It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties. … Selenious acid is the acid form of sodium selenite, a form of selenium [L1910]. Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation.

    Mixtures: I-care Multivitamin and Multimineral Tablets, Tracel Injektionslösung in einer FertigspritzeCategories: Diet, Food, and Nutrition, Alimentary Tract and Metabolism
  4. Drug

    Daclizumab

    go.drugbank.com/drugs/DB00111
    ApprovedInvestigationalWithdrawn

    in de novo allogeneic renal transplantation and used concomitantly with an immunosuppressive regimen like cyclosporine and corticosteroids in patients who are not hight immunized, for commercial reasons … the FDA in 2016 [L1746].

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: Zenapax 5mg/ml
  5. Drug

    (3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol

    go.drugbank.com/drugs/DB06943
    Experimental

    (3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol is a solid. This compound belongs to the benzenesulfonamides. … These are organic compounds containing a sulfonamide group that is S-linked to a benzene ring. This substance is known to target disintegrin and metalloproteinase domain-containing protein 17.

    Synonyms: (3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol
  6. Drug

    Hydroxide ion

    go.drugbank.com/drugs/DB14522
    Investigational

    Mixtures: OHTrust Nano Ion WaterSynonyms: Hydroxide ion
  7. Drug

    Dequalinium

    go.drugbank.com/drugs/DB04209
    Approved

    [A249255] First used as an antiseptic and disinfectant in the 1950s, dequalinium is still found in various OTC products to treat conditions of oral infections and inflammation. … Dequalinium is an antibacterial agent with multi-targeted actions. It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties.

    Categories: Antiseptics and Disinfectants, Genito Urinary System and Sex HormonesProducts: VABLYS® 10MG TABLETAS VAGINALES
  8. Drug

    Salix alba bark

    go.drugbank.com/drugs/DB14274
    Approved

    Salix alba bark is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Mixtures: Herbal Cold and Flu Formula - TabCategories: Herbs and Natural Products
  9. Drug

    Methyclothiazide

    go.drugbank.com/drugs/DB00232
    ApprovedWithdrawn

    A thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p825)

    Categories: methyclothiazide and potassium, Genito Urinary System and Sex HormonesProducts: Duretic 5mg
  10. Drug

    Carfilzomib

    go.drugbank.com/drugs/DB08889
    ApprovedInvestigational

    Carfilzomib is an injectable antineoplastic agent (IV only). Chemically, it is a modified tetrapeptidyl epoxide and an analog of epoxomicin. It is also a selective proteasome inhibitor. … FDA approved carfilzomib in July 2012 for the treatment of adults with relapsed or refractory multiple myeloma as monotherapy or combination therapy.[L39392]

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: KYPROLIS POWDER FOR SOLUTION FOR INFUSION 60MG/VIAL, Kyprolis (carfilzomib) powder for solution for infusion 60mg/vial