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Etidocaine
go.drugbank.com/drugs/DB08987ApprovedIt is an injectable local anesthetic during surgery, labor, and delivery. Etidocaine has a long duration of activity, but has the main disadvantage of increased bleeding during oral surgery.
Evalstotug
go.drugbank.com/drugs/DB19410InvestigationalEvalstotug is under investigation in clinical trial NCT05271604 (A Phase 2 Open Label Study of BA3021 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck).
Synonyms: Immunoglobulin G1 [de-448-lysine], anti-(human cytotoxic T-lymphocyte-associated protein 4) (human monoclonal BA3071 γ1-chain), disulfide with human monoclonal BA3071 κ-chain, dimer, Immunoglobulin G1-kappa, anti-[Homo sapiens CTLA4 (cytotoxic T-lymphocyte associated protein 4, CTLA-4, CD152)], monoclonal antibodyPizotifen
go.drugbank.com/drugs/DB06153Approved[A32532] It is a potent serotonin and tryptamine antagonist that has been used for migraine prevention for many years. … Pizotifen hydrochloride is an active ingredient in Sandomigran, which is used for the prophylactic management of migraines.
Categories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-1 Receptor AntagonistsAxicabtagene ciloleucel
go.drugbank.com/drugs/DB13915ApprovedInvestigationalAxicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. … can produce cytokines that efficiently kill leukemic cells _in vitro_.
Categories: Antigens, Differentiation, B-Lymphocyte, Genetically-modified Autologous T CellsSynonyms: Autologous T cells transduced with retroviral vector encoding an anti-CD-19 CD28/CD3-zeta chimeric antigen receptorSelenomethionine
go.drugbank.com/drugs/DB11142ApprovedInvestigationalIt can be produced from post-structural modifications. … *In vivo*, selenomethionine plays an essential role in acting as an antioxidant, where it depletes reactive oxygen species (ROS) and aids in the formation and recycling of glutathione, another important
Mixtures: RE FAC-x, Vital-D RxSparsentan
go.drugbank.com/drugs/DB12548ApprovedInvestigational[A257330,L45300] Sparsentan is first in its class and orally active, and was created by merging the structural elements of [irbesartan], an AT<sub>1</sub>R antagonist, and biphenylsulfonamide, an ET<sub … [L45315] The use of sparsentan may cause hepatotoxicity and embryo-fetal toxicity.
Categories: Angiotensin 2 Receptor Blocker, Dual Endothelin Type A Receptor/Ang II Subtype 1 Receptor Antagonist (DEARA)Odesivimab
go.drugbank.com/drugs/DB15900ApprovedInvestigationalEbola virus (EBOV) remains an important human pathogen within the _Ebolavirus_ genus, having been responsible for at least 17 known outbreaks with an average case fatality rate of 43.92%. … [A221825] Immune therapy using monoclonal antibodies (mAbs) is becoming an increasingly attractive therapeutic method to combat infectious diseases due to its rapid development, low toxicity, and high
DL-Methylephedrine
go.drugbank.com/drugs/DB11278ApprovedMethylephedrine is a sympathomimetic amine that appears in various over-the-counter cough and cold medications throughout the world [L2838], [L2839], [L2840].
Mixtures: Pancold SCategories: Adrenergic alpha-2 Receptor AgonistsOxyphencyclimine
go.drugbank.com/drugs/DB00383ApprovedOxyphencyclimine is an anticholinergic drug (trade name Daricon) used in treating peptic ulcers.
Categories: Heterocyclic Compounds, 1-RingProducts: ออกซี่เฟน 5, ยาเม็ด อ๊อกซีเฟนไซคลีมีน (5 มก.)Cariprazine
go.drugbank.com/drugs/DB06016ApprovedInvestigationalCariprazine is an atypical antipsychotic agent and a piperazine derivative that was first developed in Hungary. … [A247100] It works as a partial agonist at central dopamine D2, dopamine D3, and serotonin 5-HT<sub>1A</sub> receptors and as an antagonist at serotonin 5-HT<sub>2A</sub> receptors.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: trans-N-{4-[2-[4-(2,3-dichlorophenyl)piperazine-1-yl]ethyl]cyclohexyl}-N’,N’-dimethylurea hydrochloride