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Fenofibric acid
go.drugbank.com/drugs/DB13873ApprovedInvestigationalL12855] Due to its high hydrophilicity and poor absorption profile,[A32038] prodrug ,[fenofibrate], and other conjugated compounds of fenofibric acid, such as choline fenofibrate, have been developed for
Categories: Hypolipidemic Agents Indicated for Hyperlipidemia, Non-statin Hypolipidemic Agents Indicated for HyperlipidemiaFingolimod
go.drugbank.com/drugs/DB08868ApprovedInvestigational[A176474] Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting multiple sclerosis. … [L12651] Fingolimod was also studied for the treatment of COVID-19, the disease caused by infection with the SARS-CoV-2 virus.[L12654,L12657]
Categories: Experimental Unapproved Treatments for COVID-19, Sphingosine 1-phosphate Receptor ModulatorChlorphenoxamine
go.drugbank.com/drugs/DB09007ApprovedWithdrawnIt is an antihistamine and anticholinergic used to treat itching as well as for its antiparkinsonian effect.
Categories: Antihistamines for Topical Use, Antihistamines for Systemic UseClascoterone
go.drugbank.com/drugs/DB12499ApprovedInvestigational[A218771] By competing with androgens for binding to androgen receptors, clascoterone works by blocking the androgen receptor signalling cascades that promote acne pathogenesis, such as sebaceous gland … [L15621] Clascoterone is also being investigated as a novel treatment for androgenetic alopecia.[A218766]
Categories: Anti-Acne Preparations for Topical Use, Androgen Receptor InhibitorsSertaconazole
go.drugbank.com/drugs/DB01153ApprovedIt is available in topical formulations for the treatment of skin infections such as athlete's foot.
Categories: Antifungals for Topical Use, Antifungals for Dermatological UseNitazoxanide
go.drugbank.com/drugs/DB00507ApprovedInvestigationalVet approvedNitazoxanide is a first-line, standard treatment for illness caused by C. parvum or G. lamblia infection in healthy (not immunosuppressed) adults and children and may also be considered in the treatment
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseBaricitinib
go.drugbank.com/drugs/DB11817ApprovedInvestigational[A248400] The EC later approved baricitinib for the treatment of atopic dermatitis, making it the first JAK inhibitor used for this indication in Europe. … the use of baricitinib for the treatment of COVID-19 in May 2022.
Categories: Experimental Unapproved Treatments for COVID-19Luliconazole
go.drugbank.com/drugs/DB08933ApprovedInvestigationalLuliconazole is a topical antifungal agent that acts by unknown mechanisms but is postulated to involve altering the synthesis of fungi cell membranes. It was approved by the FDA (USA) in November 2013 and is marketed under the brand nam...
Categories: Antifungals for Topical Use, Antifungals for Dermatological UseFerumoxytol
go.drugbank.com/drugs/DB06215ApprovedInvestigational[L54501] The drug remains approved in the US, with a new indication being approved in October of 2025 for Ferumoxytol's use as a diagnostic agent for MRI of the brain. … In January of 2015, the EMA withdrew marketing authorisation for Rienso (ferumoxytol) due to safety concerns.
Sofosbuvir
go.drugbank.com/drugs/DB08934ApprovedInvestigationalNS5B, an RNA-dependent RNA polymerase, is essential for the transcription of Hepatitis C viral RNA and for its high replicative rate and genetic diversity [A19594]. … in combination with other antivirals for all six genotypes of Hepatitis C [L852].
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use