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Nitric oxide synthase, inducible
go.drugbank.com/bio_entities/BE0000005TargetEnzymeHumansIn macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity). … Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed:7504305, PubMed:7531687, PubMed:7544004, PubMed:7682706).
Synonyms: Inducible NO synthaseErythropoietin Resistant Anemia (EPO Resistant Anemia)
go.drugbank.com/conditions/DBCOND0161719Drugs: VadadustatSynonyms: Anemia co-occurrent and due to chronic kidney disease, Anaemia co-occurrent and due to chronic kidney diseaseRelapsed or Refractory Follicular Lymphoma
go.drugbank.com/conditions/DBCOND0071783Drugs: MosunetuzumabSynonyms: Relapsed and Refractory Follicular LymphomaVancomycin
go.drugbank.com/drugs/DB00512ApprovedInvestigationalIt is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. … caused by _Staphylococcus aureus_, including methicillin-resistant strains [LP1196].
Categories: Alimentary Tract and Metabolism, Amino Acids, Peptides, and ProteinsProducts: Vancocin Cp Add-vantage Inj 500mg/vial, Vancocin 1 g - Pulver für ein Konzentrat zur Herstellung einer Infusionslösung und einer Lösung zum EinnehmenTonsillitis Chronic
go.drugbank.com/conditions/DBCOND0113605Drugs: XibornolSynonyms: Chronic tonsillitis and adenoiditisMerbromin
go.drugbank.com/drugs/DB13392InvestigationalIt is an organomercuric disodium salt compound and a fluorescein that is available in many countries, except Switzerland, France, Germany, and the United States where the drug was withdrawn from market … due to the possibility of mercury poisoning.
Categories: Antiseptics and DisinfectantsProducts: MERBROMINA NAPibrentasvir
go.drugbank.com/drugs/DB13878ApprovedInvestigationalMavyret is also indicated for HCV genotype 1-infected patients who have been previously treated with regimens either containing an NS5A inhibitor or an NS3/4A protease inhibitor, but not both [L940]. … patients with moderate to severe kidney disease and those who are on dialysis [L940].
Mixtures: MAVIRET FILM-COATED TABLET 100MG/40MG, MAVIRET (GLECAPREVIR 100MG/ PIBRENTASVIR 40MG) FILM COATED TABLETSCategories: glecaprevir and pibrentasvirElvitegravir
go.drugbank.com/drugs/DB09101ApprovedInvestigationalElvitegravir was first licensed from Japan Tobacco in 2008 and developed by Gilead Sciences. It was FDA approved on August 27, 2012. … Because integrase is necessary for viral replication, inhibition prevents the integration of HIV-1 DNA into the host genome and thereby blocks the formation of the HIV-1 provirus and resulting propagation
Mixtures: STRIBILD 150MG/150MG/200MG/245MG FILM KAPLI TABLET, 90 ADET, STRIBILD 150MG/150MG/200MG/245MG FILM KAPLI TABLET, 30 ADETCategories: emtricitabine, tenofovir disoproxil, elvitegravir and cobicistat, emtricitabine, tenofovir alafenamide, elvitegravir and cobicistatAcute Pelvic inflammatory disease
go.drugbank.com/conditions/DBCOND0022868Drugs: OfloxacinSynonyms: Acute pelvic inflammatory disease of the female pelvic organs and tissues, Acute pelvic inflammatory disease of the female pelvic organs AND/OR tissues