Search
Triclocarban
go.drugbank.com/drugs/DB11155ApprovedTriclocarban, with the chemical formula C13H9Cl3N2O [L2675] is an antibacterial agent that is particularly effective against Gram-positive bacteria such as *Staphylococcus aureus*. … It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products.
Aminophenazone
go.drugbank.com/drugs/DB01424ApprovedWithdrawnAminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries a risk of agranulocytosis. … The FDA suspended the use of aminophenazone due to its association with agranulocytosis, a life-threatening side effect.[A254242,L43942]
Sutilain
go.drugbank.com/drugs/DB09379ApprovedWithdrawnSutilain contains proteolytic enzymes derived from _Bacillus subtilis_ and it is available as a cream-colored odorless powder. … Sutilain is a member of the keratase family which includes agents such as papain. It is able to dissolve the intercellular matrix which helps with desquamation.
Magnesium carbonate
go.drugbank.com/drugs/DB09481ApprovedMagnesium carbonate, also known as magnesite, is a common over the counter remedy for heartburn and upset stomach caused by overproduction of acid in the stomach [FDA Label].
Categories: Compounds used in a research, industrial, or household settingPenpulimab
go.drugbank.com/drugs/DB16747ApprovedInvestigationalPenpulimab is a humanized monoclonal IgG1 antibody targeting the immune checkpoint programmed death receptor-1 (PD-1). … The use of an IgG1 backbone - as opposed to an IgG4 backbone as is typical in other anti-PD-1 antibodies like [nivolumab] - is intended to reduce the risk of immune-related adverse events.
Categories: Programmed Death Receptor-1 Blocking AntibodyIbrutinib
go.drugbank.com/drugs/DB09053ApprovedInvestigationalIt is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. … Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase.
Quizartinib
go.drugbank.com/drugs/DB12874ApprovedInvestigationalmaintenance monotherapy resulted in a 22% reduction in the risk of death. … Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug developed specifically targeting FLT3, as other agents with FLT3 inhibition activities were investigated
Iophendylate
go.drugbank.com/drugs/DB01187ApprovedIophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization. Iophendylate is a myelographic oil-ester (U.S. Patent 2,348,231). … In 1942 Van Wagenen (a neurosurgical colleague of Warrens, at the University of Rochester) identified Iophendylate as causing chemical meningitis in 30 patients where "space-displacing masses within the
Categories: Compounds used in a research, industrial, or household settingArbutin
go.drugbank.com/drugs/DB11217ApprovedIt has also been used as an anti-infective for the urinary system as well as a diuretic [F43]. … Most commonly, it is an active ingredient in skincare and cosmetic products as a skin-lightening agent for the prevention of melanin formation in various skin conditions that involve cutaneous hyperpigmentation
Products: Obagi Nu-Derm Clear FxIopromide
go.drugbank.com/drugs/DB09156ApprovedIt functions as a contrast agent by opacifying blood vessels in the flow path of the contrast agent, permitting radiographic visualization of the internal structures until significant hemodilution occurs … Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration.
Categories: Compounds used in a research, industrial, or household setting