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Displaying results 1821 - 1830 of 9667 in total
  1. Drug

    Hexocyclium

    go.drugbank.com/drugs/DB06787
    Approved

    It was once available under the tradename Tral marketed by Abbvie Inc. but has been discontinued. … Hexocyclium is a muscarinic acetylcholine receptor antagonist which was presumably used in the treatment of gastric ulcer or diarrhea.

  2. Drug

    Vanzacaftor

    go.drugbank.com/drugs/DB18373
    ApprovedInvestigational

    It is used alongside other CFTR correctors and CFTR potentiators to increase the quantity and function of CFTR at the cell surface in patients with cystic fibrosis. … [L52275,A179677] Vanzacaftor was first approved by the US FDA in December 2024 in combination with another CFTR corrector - [tezacaftor], which binds to a different site than vanzacaftor - and [deutivacaftor

  3. Drug

    Tinzaparin

    go.drugbank.com/drugs/DB06822
    ApprovedInvestigational

    It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. … LMWHs are less effective at inactivating factor IIa due to their shorter length compared to unfractionated heparin.

  4. Drug

    Taurine

    go.drugbank.com/drugs/DB01956
    ApprovedInvestigationalNutraceutical

    It plays important role in essential biological processes.

    Mixtures: LEVAMIN PAD, SMOFKABIVEN EF
  5. Indication

    Pulmonary arterial hypertension WHO functional class I

    go.drugbank.com/conditions/DBCOND0160108
    Drugs: Ambrisentan · Selexipag · Sotatercept
    Synonyms: PAH WHO Group I, Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)
  6. Drug

    Atoltivimab

    go.drugbank.com/drugs/DB15898
    ApprovedInvestigational

    INMAZEB™ is produced by Regeneron Pharmaceuticals and was granted FDA approval on October 14, 2020.[L17320] … Ebola virus (EBOV) remains an important human pathogen within the _Ebolavirus_ genus, having been responsible for at least 17 known outbreaks with an average case fatality rate of 43.92%.

  7. Drug

    Florquinitau (18F)

    go.drugbank.com/drugs/DB19215
    Approved

    Florquinitau F 18 is a radioactive diagnostic drug used as a fluorine-18–labeled positron emission tomography (PET) tracer. … [L64052,L64053] It is the second fluorine-18 tau PET imaging agent approved in the United States, after flortaucipir (Tauvid), which was approved in 2020.[L64054,L14114]

  8. Drug

    Calcium polycarbophil

    go.drugbank.com/drugs/DB14684
    Approved

    Based on its chemical structure, it is a synthetic polymer of polyacrylic acid cross-linked with divinyl glycol presenting a calcium atom as a counter-ion. … Less gas and bloating compared to psyllium laxative products, but can cause heartburn, and belly cramps. It is insoluble in water, dilute acids, and dilute alkali.

    Products: Equalactin - Tab 625mg, Good Neighbor Pharmacy Fiber-Caps Fiber Laxative Stimulant Free
  9. Drug

    Altretamine

    go.drugbank.com/drugs/DB00488
    ApprovedWithdrawn

    An alkylating agent proposed as an antineoplastic. It also acts as a chemosterilant for male houseflies and other insects.

  10. Drug

    Ajmaline

    go.drugbank.com/drugs/DB01426
    ApprovedWithdrawn

    It has also been used for many years as a drug to challenge the conduction system of the heart in cases of bundle branch block and syncope. … It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials.