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Givosiran
go.drugbank.com/drugs/DB15066Approved[L10202] It is manufactured by Alnylam Pharmaceuticals and was first approved for use in the United States in November 2019 for the treatment of adults with acute hepatic porphyria, a genetic disorder … involved non-therapeutic measures (e.g. trigger avoidance), intravenous [hemin] for the treatment of attacks, and liver transplantation in refractory cases.
Etryptamine
go.drugbank.com/drugs/DB01546ApprovedIllicitWithdrawnIn the 1960's, alpha-ethyltryptamine (αET), a non hydrazine reversible monoamine oxidase inhibitor, was developed in the United States by the Upjohn chemical company for use as an antidepressant. αET was
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesCyclacillin
go.drugbank.com/drugs/DB01000ApprovedA cyclohexylamido analog of penicillanic acid.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseVilobelimab
go.drugbank.com/drugs/DB16416ApprovedInvestigationalThe drug is not yet fully approved for this condition.[L45849] … [L45839] In April 2023, the FDA issued an emergency use authorization (EUA) for vilobelimab for the treatment of COVID-19 in hospitalized adults requiring mechanical ventilation or artificial life support
Categories: Experimental Unapproved Treatments for COVID-19Sulfamethazine
go.drugbank.com/drugs/DB01582ApprovedVet approvedWithdrawnA sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseCeforanide
go.drugbank.com/drugs/DB00923ApprovedCeforanide is administered parenterally. It has a longer elimination half-life than any currently available cephalosporin. Its activity is very similar to that of cefamandole, another second-generation cephalosporin antibiotic, except th...
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseHexaminolevulinate
go.drugbank.com/drugs/DB06261ApprovedInvestigationalFood and Drug Administration (FDA) granted approval for hexaminolevulinate hydrochloride (Cysview for Intravesical Solution, Photocure ASA), as an optical imaging agent for use in combination with the … Karl Storz Photodynamic Diagnostic D-Light C (PDD) System for cystoscopic detection of non-muscle invasive papillary cancer of the bladder for patients suspected or known to have lesion(s) on the basis
Alitretinoin
go.drugbank.com/drugs/DB00523ApprovedIt has also been approved for use in promyelocytic leukemia (leukemia, promyelocytic, acute). … Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess of tretinoin can be teratogenic.
Categories: Retinoids for cancer treatment, Agents for Dermatitis, Excluding CorticosteroidsStannous chloride
go.drugbank.com/drugs/DB11056ApprovedThese complexes localize primarily in bone (40-50%) and infracted myocardium (0.01-0.02%/g of tissue) allowing for imaging of areas of altered osteogenesis or necrotic heart tissue [FDA Label].
Demeclocycline
go.drugbank.com/drugs/DB00618ApprovedBecause it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.
Categories: Antibiotics for Topical Use, Antibacterials for Systemic Use