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Displaying results 1841 - 1850 of 10000 in total
  1. Drug

    Mifamurtide

    go.drugbank.com/drugs/DB13615
    ApprovedInvestigational

    Also called L-MTP-PE, mifamurtide may be a liposomal form of of the active ingredient MTP-PE, which is a synthetic, less pyrogenic, and longer-acting derivative of muramyl dipeptide (MDP). … As a liposomal formulation, mifamurtide demonstrates an enhanced tumoricidal effect and improved safety profile [A31745]. Mifamurtide is marketed in Europe as Mepact for intravenous infusion.

    Products: MEPACT 4 MG INFÜZYONLUK DISPERSIYON KONSANTRESI IÇIN TOZ ,FLAKON, 1 ADET
  2. Drug

    Vindesine

    go.drugbank.com/drugs/DB00309
    ApprovedInvestigationalWithdrawn

    Vinblastine derivative with antineoplastic activity against cancer. Major side effects are myelosuppression and neurotoxicity. Vindesine is used extensively in chemotherapy protocols (antineoplastic combined chemotherapy protocols).

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: Eldisin 5 mg Trockenstechampulle, Eldisine Inj 5mg/2ml
  3. Drug

    Brodalumab

    go.drugbank.com/drugs/DB11776
    ApprovedInvestigational

    Brodalumab has been used in trials studying the treatment of Asthma, Psoriasis, Crohn's Disease, Psoriatic Arthritis, and Rheumatoid Arthritis. Brodalumab was FDA approved in February, 2017 as Siliq for the treatment of moderate-to-sever...

    Categories: Interleukin-17 Receptor A Antagonist, Interleukin 17 Receptor A AntagonistsProducts: LUMICEF SUBCUTANEOUS INJECTION 210 MG SYRINGE
  4. Drug

    Lynestrenol

    go.drugbank.com/drugs/DB12474
    ApprovedWithdrawn

    Lynestrenol is a progestin and prodrug of [norethisterone].

    Products: ORGAMETRİL 5 MG TABLET, 30 ADET
  5. Drug

    Dimercaptosuccinic acid

    go.drugbank.com/drugs/DB14089
    ApprovedInvestigational

    Categories: Compounds used in a research, industrial, or household settingProducts: MON.DMSA KIT 1 MG IV ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 5 ADET
  6. Drug

    Dactinomycin

    go.drugbank.com/drugs/DB00970
    ApprovedInvestigational

    A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. … As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)

    Categories: P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: 2-amino-N,N'-bis(hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo(2,1-i)(1,4,7,10,13)oxatetra-azacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide, 3H-PHENOXAZINE-1,9-DICARBOXAMIDE, 2-AMINO-N,N'-BIS(HEXADECAHYDRO-6,13-DIISOPROPYL-2,5,9-TRIMETHYL-1,4,7,11,14-PENTAOXO-1H-PYRROLO(2,1-I)(1,4,7,10,13)OXATETRAAZACYCLOHEXADECIN-10-YL)-4,6-DIMETHYL-3-OXO-
  7. Drug

    Brotizolam

    go.drugbank.com/drugs/DB09017
    ApprovedWithdrawn

    Brotizolam is a sedative-hypnotic thienodiazepine drug which is a benzodiazepine analog. It demonstrates anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant effects.

    International brands: Brotizolam MProducts: Lendorm 0,25 mg - Tabletten, BROTIZOLAM EG
  8. Drug

    Teniposide

    go.drugbank.com/drugs/DB00444
    ApprovedInvestigational

    Teniposide is a semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA.

    Categories: Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexInternational brands: Bang Lai
  9. Drug

    Carbopol 974P

    go.drugbank.com/drugs/DB05384
    ApprovedWithdrawn

    Carbopol 974P is a highly carboxylated polymer composed of lightly cross-linked polyacrylic acid with a broad-spectrum mechanism based on acidification of pathogens. … It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted pregnancies.

    Categories: Compounds used in a research, industrial, or household settingProducts: SICCAFLUID® 2.5 MG/G GEL OFTALMICO, LIQUIGEL UD 2.5MG/G EINZEL
  10. Drug

    Ceftobiprole medocaril

    go.drugbank.com/drugs/DB14733
    Approved

    Ceftobiprole medocaril is a prodrug of [ceftobiprole], a fifth-generation semisynthetic cephalosporin antibacterial. … Ceftobiprole is a broad-spectrum agent with demonstrated activity against both Gram-positive and Gram-negative bacteria, including antibiotic-resistant strains of _Staphylcoccus aureus_ (methicillin-resistant

    Products: Zevtera 500 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung